[HTML][HTML] Design of therapeutic biomaterials to control inflammation
Inflammation plays an important role in the response to danger signals arising from damage
to our body and in restoring homeostasis. Dysregulated inflammatory responses occur in …
to our body and in restoring homeostasis. Dysregulated inflammatory responses occur in …
The tumor EPR effect for cancer drug delivery: Current status, limitations, and alternatives
Over the past three decades, the enhanced permeability and retention (EPR) effect has
been considered the basis of tumor-targeted drug delivery. Various cancer nanomedicines …
been considered the basis of tumor-targeted drug delivery. Various cancer nanomedicines …
Size-Dependent In Vivo Transport of Nanoparticles: Implications for Delivery, Targeting, and Clearance
Understanding the in vivo transport of nanoparticles provides guidelines for designing
nanomedicines with higher efficacy and fewer side effects. Among many factors, the size of …
nanomedicines with higher efficacy and fewer side effects. Among many factors, the size of …
Chemical and biophysical signatures of the protein corona in nanomedicine
J Ren, N Andrikopoulos, K Velonia… - Journal of the …, 2022 - ACS Publications
An inconvenient hurdle in the practice of nanomedicine is the protein corona, a spontaneous
collection of biomolecular species by nanoparticles in living systems. The protein corona is …
collection of biomolecular species by nanoparticles in living systems. The protein corona is …
Tumor abnormality-oriented nanomedicine design
Anticancer nanomedicines have been proven effective in mitigating the side effects of
chemotherapeutic drugs. However, challenges remain in augmenting their therapeutic …
chemotherapeutic drugs. However, challenges remain in augmenting their therapeutic …
Stimuli‐responsive nanoparticles for controlled drug delivery in synergistic cancer immunotherapy
J Zhang, Y Lin, Z Lin, Q Wei, J Qian, R Ruan… - Advanced …, 2022 - Wiley Online Library
Cancer immunotherapy has achieved promising clinical progress over the recent years for
its potential to treat metastatic tumors and inhibit their recurrences effectively. However, low …
its potential to treat metastatic tumors and inhibit their recurrences effectively. However, low …
Near-infrared photoactivated nanomedicines for photothermal synergistic cancer therapy
Cancer nanomedicines have provided promising treatment strategies for the regression of
several types of cancer, although there still exists a need for significant advances to improve …
several types of cancer, although there still exists a need for significant advances to improve …
[HTML][HTML] Nanopolystyrene translocation and fetal deposition after acute lung exposure during late-stage pregnancy
SB Fournier, JN D'Errico, DS Adler, S Kollontzi… - Particle and Fibre …, 2020 - Springer
Abstract Background Plastic is everywhere. It is used in food packaging, storage containers,
electronics, furniture, clothing, and common single-use disposable items. Microplastic and …
electronics, furniture, clothing, and common single-use disposable items. Microplastic and …
[HTML][HTML] Engineering tumoral vascular leakiness with gold nanoparticles
Delivering cancer therapeutics to tumors necessitates their escape from the surrounding
blood vessels. Tumor vasculatures are not always sufficiently leaky. Herein, we engineer …
blood vessels. Tumor vasculatures are not always sufficiently leaky. Herein, we engineer …
[HTML][HTML] Noncancerous disease-targeting AIEgens
Y Duo, G Luo, W Zhang, R Wang, GG Xiao… - Chemical Society …, 2023 - pubs.rsc.org
Noncancerous diseases include a wide plethora of medical conditions beyond cancer and
are a major cause of mortality around the world. Despite progresses in clinical research …
are a major cause of mortality around the world. Despite progresses in clinical research …