Antiphospholipid antibodies (aPL) are both diagnostic markers for, and pathogenic drivers
of, antiphospholipid syndrome (APS). Although the presence of aPL is a necessary pre …

Annexin A2 is a pleiotropic calcium-and anionic phospholipid-binding protein that exists as
a monomer and as a heterotetrameric complex with the plasminogen receptor protein …

The antiphospholipid syndrome (APS) is characterized by thrombosis and/or pregnancy
morbidity in the presence of antiphospholipid antibodies, including anti-β2-glycoprotein-I …

Objective Antiphospholipid antibodies (aPL), especially those targeting β2‐glycoprotein I
(β2GPI), are well known to activate endothelial cells, monocytes, and platelets, with …

Objective While endothelial dysfunction has been implicated in the widespread
thromboinflammatory complications of COVID‐19, the upstream mediators of …

Abstract Beta-2-Glycoprotein I (β2GPI) plays a number of essential roles throughout the
body. β2GPI, C-reactive protein and thrombomodulin are the only three proteins that …

The antiphospholipid syndrome (APS) is characterized by thrombosis and pregnancy
morbidity in the presence of antiphospholipid antibodies (aPL). Complement is a system of …

Abstract Coronavirus disease 2019 (COVID-19) is still an ongoing pandemic worldwide.
COVID-19 is an age-related disease with a higher risk of organ dysfunction and mortality in …

Antiphospholipid syndrome (APS) is an acquired thromboinflammatory disorder
characterized by the presence of antiphospholipid antibodies as well as an increased …

Antiphospholipid antibodies are a heterogeneous group of autoantibodies that have clear
associations with thrombosis and pregnancy morbidity, and which together constitute the …