[HTML][HTML] The mechanism and therapy of aortic aneurysms

J Gao, H Cao, G Hu, Y Wu, Y Xu, H Cui, HS Lu… - Signal transduction and …, 2023 - nature.com
Aortic aneurysm is a chronic aortic disease affected by many factors. Although it is generally
asymptomatic, it poses a significant threat to human life due to a high risk of rupture …

Management of acute aortic dissection

CA Nienaber, RE Clough - The Lancet, 2015 - thelancet.com
A new appraisal of the management of acute aortic dissection is timely because of recent
developments in diagnostic strategies (including biomarkers and imaging), endograft …

Endovascular repair of type B aortic dissection: long-term results of the randomized investigation of stent grafts in aortic dissection trial

CA Nienaber, S Kische, H Rousseau… - Circulation …, 2013 - Am Heart Assoc
Background—Thoracic endovascular aortic repair (TEVAR) represents a therapeutic
concept for type B aortic dissection. Long-term outcomes and morphology after TEVAR for …

Population-based study of incidence and outcome of acute aortic dissection and premorbid risk factor control: 10-year results from the Oxford Vascular Study

DPJ Howard, A Banerjee, JF Fairhead, J Perkins… - Circulation, 2013 - Am Heart Assoc
Background—Acute aortic dissection is a preventable life-threatening condition. However,
there have been no prospective population-based studies of incidence or outcome to inform …

Risk profiles for aortic dissection and ruptured or surgically treated aneurysms: a prospective cohort study

M Landenhed, G Engström, A Gottsäter… - Journal of the …, 2015 - Am Heart Assoc
Background Community screening to guide preventive interventions for acute aortic disease
has been recommended in high‐risk individuals. We sought to prospectively assess risk …

The incidence and mortality of acute thoracic aortic dissection: results from a whole nation study

IH Melvinsdottir, SH Lund, BA Agnarsson… - European Journal of …, 2016 - academic.oup.com
OBJECTIVES Acute thoracic aortic dissection (ATAD) is a devastating condition associated
with a high mortality rate. Recent reports suggest that its incidence is rising. Utilizing …

Common variation in PHACTR1 is associated with susceptibility to cervical artery dissection

S Debette, Y Kamatani, TM Metso, M Kloss… - Nature …, 2015 - nature.com
Cervical artery dissection (CeAD), a mural hematoma in a carotid or vertebral artery, is a
major cause of ischemic stroke in young adults although relatively uncommon in the general …

Neutrophil-derived matrix metalloproteinase 9 triggers acute aortic dissection

T Kurihara, R Shimizu-Hirota, M Shimoda, T Adachi… - Circulation, 2012 - Am Heart Assoc
Background—Acute aortic dissection (AAD) is a life-threatening vascular disease without
effective pharmaceutical therapy. Matrix metalloproteinases (MMPs) are implicated in the …

Targeting endothelial tight junctions to predict and protect thoracic aortic aneurysm and dissection

X Yang, C Xu, F Yao, Q Ding, H Liu, C Luo… - European Heart …, 2023 - academic.oup.com
Aims Whether changes in endothelial tight junctions (TJs) lead to the formation of thoracic
aortic aneurysm and dissection (TAAD) and serve as an early indicator and therapeutic …

Molecular mechanisms of thoracic aortic dissection

D Wu, YH Shen, L Russell, JS Coselli… - Journal of Surgical …, 2013 - Elsevier
Thoracic aortic dissection (TAD) is a highly lethal vascular disease. In many patients with
TAD, the aorta progressively dilates and ultimately ruptures. Dissection formation …