Cellular mechanotransduction, a critical regulator of numerous biological processes, is the
conversion from mechanical signals to biochemical signals regarding cell activities and …

There is increasing evidence that chondrocytes within articular cartilage are affected by
endogenous force-related electrical potentials. Furthermore, electrical stimulation (ES) …

Peripheral nerve injury is a complex and challenging medical condition due to the limited
ability of nerves to regenerate, resulting in the loss of both sensory and motor function …

Repair of peripheral nerve crush injury remains a major clinical challenge. Currently, oral or
intravenous neurotrophic drugs are the main treatment for peripheral nerve crush injury; …

Tissue-engineered nerve guidance conduits (NGCs) are a viable clinical alternative to
autografts and allografts and have been widely used to treat peripheral nerve injuries (PNIs) …

The latest advancements in the field of manufacturing for biomedicine, digital health,
targeted therapy, and personalized medicine have fuelled the fabrication of smart medical …

Traumatic nerve injuries are nowadays a significant clinical challenge and new substitutes
with adequate biological and mechanical properties are in need. In this context, fibrin …

It has increasingly been recognized that electrical currents play a pivotal role in cell
migration and tissue repair, in a process named “galvanotaxis”. In this review, we summarize …

Addressing the challenge of promoting directional axonal regeneration in a hostile astrocytic
scar, which often impedes recovery following spinal cord injury (SCI), remains a daunting …

Bioactive macromolecular drugs known as Growth Factors (GFs), approved by the Food and
Drug Administration (FDA), have found successful application in clinical practice. They hold …