The role of lipids in cancer progression and metastasis
M Martin-Perez, U Urdiroz-Urricelqui, C Bigas… - Cell metabolism, 2022 - cell.com
Lipids have essential biological functions in the body (eg, providing energy storage, acting
as a signaling molecule, and being a structural component of membranes); however, an …
as a signaling molecule, and being a structural component of membranes); however, an …
[HTML][HTML] Metabolic reprogramming of colorectal cancer cells and the microenvironment: implication for therapy
M Nenkov, Y Ma, N Gaßler, Y Chen - International journal of molecular …, 2021 - mdpi.com
Colorectal carcinoma (CRC) is one of the most frequently diagnosed carcinomas and one of
the leading causes of cancer-related death worldwide. Metabolic reprogramming, a hallmark …
the leading causes of cancer-related death worldwide. Metabolic reprogramming, a hallmark …
[HTML][HTML] The fatty acid receptor CD36 promotes HCC progression through activating Src/PI3K/AKT axis-dependent aerobic glycolysis
X Luo, E Zheng, L Wei, H Zeng, H Qin, X Zhang… - Cell death & …, 2021 - nature.com
Metabolic reprogramming is a new hallmark of cancer but it remains poorly defined in
hepatocellular carcinogenesis (HCC). The fatty acid receptor CD36 is associated with both …
hepatocellular carcinogenesis (HCC). The fatty acid receptor CD36 is associated with both …
[HTML][HTML] The role of CD36 in cancer progression and its value as a therapeutic target
WW Feng, HT Zuppe, M Kurokawa - Cells, 2023 - mdpi.com
Cluster of differentiation 36 (CD36) is a cell surface scavenger receptor that plays critical
roles in many different types of cancer, notably breast, brain, and ovarian cancers. While it is …
roles in many different types of cancer, notably breast, brain, and ovarian cancers. While it is …
[HTML][HTML] Fatty acids and evolving roles of their proteins in neurological, cardiovascular disorders and cancers
The dysregulation of fat metabolism is involved in various disorders, including
neurodegenerative, cardiovascular, and cancers. The uptake of long-chain fatty acids …
neurodegenerative, cardiovascular, and cancers. The uptake of long-chain fatty acids …
[HTML][HTML] Role of CD36 in cancer progression, stemness, and targeting
SL Guerrero-Rodríguez, C Mata-Cruz… - Frontiers in Cell and …, 2022 - frontiersin.org
CD36 is highly expressed in diverse tumor types and its expression correlates with
advanced stages, poor prognosis, and reduced survival. In cancer cells, CD36: 1) increases …
advanced stages, poor prognosis, and reduced survival. In cancer cells, CD36: 1) increases …
CD36: an emerging therapeutic target for cancer and its molecular mechanisms
C Ruan, Y Meng, H Song - Journal of Cancer Research and Clinical …, 2022 - Springer
Tumor cells need to rewire their metabolic pathways to regulate the nutrient uptake and
metabolism to sustain the energy production. Lipids are important components of energy …
metabolism to sustain the energy production. Lipids are important components of energy …
[HTML][HTML] Mitochondrial and metabolic alterations in cancer cells
J Di Gregorio, S Petricca, R Iorio, E Toniato… - European journal of cell …, 2022 - Elsevier
Metabolic alterations have been observed in many cancer types. The deregulated
metabolism has thus become an emerging hallmark of the disease, where the metabolism is …
metabolism has thus become an emerging hallmark of the disease, where the metabolism is …
[HTML][HTML] Upregulation of CD36, a fatty acid translocase, promotes colorectal cancer metastasis by increasing MMP28 and decreasing E-cadherin expression
J Drury, PG Rychahou, CO Kelson, ME Geisen, Y Wu… - Cancers, 2022 - mdpi.com
Simple Summary Colorectal cancer is the second leading cause of cancer-related death in
the world. Upregulation of fatty acid metabolism is a hallmark of cancer and recent studies …
the world. Upregulation of fatty acid metabolism is a hallmark of cancer and recent studies …
[HTML][HTML] Reprogrammed lipid metabolism and the lipid-associated hallmarks of colorectal cancer
Simple Summary Colorectal cancer (CRC) is the third-most diagnosed cancer and the
second-leading cause of cancer-related deaths worldwide. Limitations in early and accurate …
second-leading cause of cancer-related deaths worldwide. Limitations in early and accurate …