Estrogens have been implicated in the pathogenesis of various cancers, with increasing
concern regarding the overall rising incidence of disease and exposure to environmental …

The greater prevalence and incidence of Parkinson's disease (PD) in men suggest a
beneficial effect of sex hormones. Neuroactive steroids have neuroprotective activities thus …

The G protein-coupled estrogen receptor (GPER) mediates estrogen action in different
pathophysiological conditions, including cancer. GPER expression and signaling have been …

Background/Aim: A wide variety of answers can be found regarding the question of whether
G-protein-coupled estrogen receptor 1 (GPER1) is tumor supportive or tumor suppressive. In …

Estrogens and their role in cancer are well-studied, and some cancer types are classified in
terms of their response to them. In recent years, a G protein-coupled estrogen receptor …

Nonalcoholic fatty liver disease (NAFLD), especially nonalcoholic steatohepatitis (NASH),
has emerged as a prevalent cause of liver cirrhosis and hepatocellular carcinoma, posing …

Chronic pain is a worldwide refractory health disease that causes major financial and
emotional burdens and that is devastating for individuals and society. One primary source of …

Estrogens induce several regulatory signals in the nervous system that are mainly mediated
through estrogen receptors (ERs). ERs are largely expressed in the nervous system, yet the …

Aims Estrogen-regulated pathways are involved in the etiology and progression of epithelial
ovarian cancer (EOC), but the relative contribution of estrogen receptor isoforms is unclear …

OBJECTIVE The relationship between patient and meningioma characteristics and hormone
receptors (HRs) of progesterone, estrogen, and androgen remains poorly defined despite …