During angiogenesis, αv integrins are overexpressed on the endothelial cell surface to
facilitate the growth and survival of newly forming vessels. Accordingly, blocking αv integrin …

The surface of a cell represents a collection of macromolecules, which provides the cell with
a unique cellular landscape specific to the type and state of the cell. Ligands that …

As effective ways to regulate protein levels, targeted protein degradation technologies have
attracted great attention in recent years. Here, we established a novel integrin-facilitated …

Molecular imaging techniques are now indispensable tools in modern diagnostics, because
they are highly specific and can provide biological information at the molecular level in living …

Photosensitizers to precise target and change fluorescence upon light illumination could
accurately self-report where and when the photosensitizers work, enabling us to visualize …

Integrin αvβ3 is restrictedly expressed on angiogenic blood vessels and tumour cells. It
plays a key role in angiogenesis for tumour growth and metastasis. RGD peptide can …

Cancer has become the number one cause of death amongst Americans, killing
approximately 1,600 people per day. Novel methods for early detection and the …

Cellular and tissue imaging in the near‐infrared (NIR) wavelengths between 700 and 900
nm is advantageous for in vivo imaging because of the low absorption of biological …

Receptor change induced by ligand binding is a new issue to face in the field of targeted
delivery. Receptor clustering, the main pattern of receptor changes, decreases the affinity …

In developed countries, cancer is the second leading cause of death, being only surpassed
by cardiovascular diseases. To develop tumor-targeted tools to localize and treat cancer at …