miRNAs insights into rheumatoid arthritis: Favorable and detrimental aspects of key performers

AS Doghish, A Ismail, HA El-Mahdy, SY Elkhawaga… - Life Sciences, 2023 - Elsevier
Rheumatoid arthritis (RA) is a severe autoimmune inflammation that mostly affects the joints.
It's a multifactorial disease. Its clinical picture depends on genetic and epigenetic factors …

Inflammation in the pathophysiology of neuropathic pain

C Sommer, M Leinders, N Üçeyler - Pain, 2018 - journals.lww.com
2. Methods This is a narrative review based on the authors' research and on that of groups
working in the same area. Given the vast amount of data in the field, it is not possible to …

MicroRNAs in rheumatoid arthritis: From pathogenesis to clinical impact

G Evangelatos, GE Fragoulis, V Koulouri… - Autoimmunity reviews, 2019 - Elsevier
Over the last decade, many epigenetic mechanisms that contribute in the pathogenesis of
autoimmune disorders have been revealed. MicroRNAs (miRNAs) are small, non-coding …

Specific miRNA disease biomarkers in blood, serum and plasma: challenges and prospects

C Backes, E Meese, A Keller - Molecular diagnosis & therapy, 2016 - Springer
Significant effort has been devoted to discovering microRNA (miRNA) disease biomarkers.
In particular, miRNAs in whole blood or specific blood components are candidates for …

MicroRNAs as peripheral biomarkers in aging and age-related diseases

S Kumar, M Vijayan, JS Bhatti, PH Reddy - Progress in molecular biology …, 2017 - Elsevier
MicroRNAs (miRNAs) are found in the circulatory biofluids considering the important
molecules for biomarker study in aging and age-related diseases. Blood or blood …

Non-coding RNAs in rheumatoid arthritis: from bench to bedside

J Wang, S Yan, J Yang, H Lu, D Xu… - Frontiers in immunology, 2020 - frontiersin.org
Rheumatoid arthritis is a common systemic and autoimmune disease characterized by
symmetrical and inflammatory destruction of distal joints. Its primary pathological characters …

Identification of novel rheumatoid arthritis-associated MiRNA-204-5p from plasma exosomes

LF Wu, Q Zhang, XB Mo, J Lin, YL Wu, X Lu… - … & Molecular Medicine, 2022 - nature.com
Rheumatoid arthritis (RA) is an autoimmune disease characterized by infiltration of immune
cells in the synovium. However, the crosstalk of immune cells and synovial fibroblasts is still …

MicroRNA expression profiles and type 1 diabetes mellitus: systematic review and bioinformatic analysis

TS Assmann, M Recamonde-Mendoza… - Endocrine …, 2017 - ec.bioscientifica.com
Growing evidence indicates that microRNAs (miRNAs) have a key role in processes
involved in type 1 diabetes mellitus (T1DM) pathogenesis, including immune system …

DNA methylation as a future therapeutic and diagnostic target in rheumatoid arthritis

M Ciechomska, L Roszkowski, W Maslinski - Cells, 2019 - mdpi.com
Rheumatoid arthritis (RA) is a long-term autoimmune disease of unknown etiology that leads
to progressive joint destruction and ultimately to disability. RA affects as much as 1% of the …

Comprehensive overview of microRNA function in rheumatoid arthritis

X Peng, Q Wang, W Li, G Ge, J Peng, Y Xu, H Yang… - Bone Research, 2023 - nature.com
MicroRNAs (miRNAs), a class of endogenous single-stranded short noncoding RNAs, have
emerged as vital epigenetic regulators of both pathological and physiological processes in …