Osteocalcin (Ocn), which is specifically produced by osteoblasts, and is the most abundant
non-collagenous protein in bone, was demonstrated to inhibit bone formation and function …

The major focus of this Review is on the mechanisms of islet β cell failure in the
pathogenesis of obesity-associated type 2 diabetes (T2D). As this demise occurs within the …

Exercise can prevent and improve the pathophysiology of diseases and promote healthy
aging. Thus, understanding the mechanisms that regulate the beneficial effects of exercise …

The objective of this study was to determine the optimal conditions under which to assess
glucose tolerance in chow-and high-fat-fed C57BL/6J mice. Mice were fed either chow or …

Mammals expend energy in many ways, including basic cellular maintenance and repair,
digestion, thermoregulation, locomotion, growth and reproduction. These processes can …

Suppression of mitochondrial function promoting proliferation and apoptosis suppression
has been described in the pulmonary arteries and extrapulmonary tissues in pulmonary …

OBJECTIVE—To characterize differences in whole-body glucose metabolism between
commonly used inbred mouse strains. RESEARCH DESIGN AND METHODS …

Accumulating evidence indicates integration of dopamine function with metabolic signals,
highlighting a potential role for dopamine in energy balance, frequently construed as …

The aim of the present study was to investigate the short-and long-term effects of a high-fat
Western diet (WD) on intake, storage, expenditure, and fecal loss of energy as well as effects …

The increasing production of genetically-modified mouse models has necessitated studies
to determine the inherent physiological characteristics of commonly used mouse strains. In …