Enzyme-free dynamic DNA reaction networks for on-demand bioanalysis and bioimaging

S He, J Shang, Y He, F Wang - Accounts of Chemical Research, 2024 - ACS Publications
Conspectus The pursuit of in-depth studying the nature and law of life activity has been
dominating current research fields, ranging from fundamental biological studies to …

A Smart Deoxyribozyme‐Programmable Catalytic DNA Circuit for High‐Contrast MicroRNA Imaging

Y He, Q Wang, C Hong, R Li, J Shang, S Yu… - Angewandte …, 2023 - Wiley Online Library
Synthetic catalytic DNA circuits have been recognized as a promising signal amplification
toolbox for sensitive intracellular imaging, yet their selectivity and efficiency are always …

Recent advances in DNA-based molecular devices and their applications in cancer diagnosis

S Yang, R Zhu, S Wang, Y Xiong, G Zhou, Y Cao… - Coordination Chemistry …, 2023 - Elsevier
Cancer is one of the leading causes of death worldwide and poses a great threat to human
health. In the past few years, diverse molecular devices have been constructed by using …

Modular DNA tetrahedron nanomachine-guided dual-responsive hybridization chain reactions for discernible bivariate assay and cell imaging

C Yang, Y Shi, Y Zhang, J He, M Li, W Huang… - Analytical …, 2023 - ACS Publications
Engineering of multivariate biosensing and imaging platforms involved in disease plays a
vital role in effectively discerning cancer cells from normal cells and facilitating reliable …

Cascaded, feedback-driven, and spatially localized emergence of constitutional dynamic networks driven by enzyme-free catalytic DNA circuits

Z Zhou, N Lin, Y Ouyang, S Liu, Y Zhang… - Journal of the …, 2023 - ACS Publications
The enzyme-free catalytic hairpin assembly (CHA) process is introduced as a functional
reaction module for guided, high-throughput, emergence, and evolution of constitutional …

Fluorescent features and applicable biosensing of a core–shell Ag nanocluster shielded by a DNA tetrahedral nanocage

J He, S Luo, H Deng, C Yang, Y Zhang, M Li… - Analytical …, 2023 - ACS Publications
The DNA frame structure as a natural shell to stably shield the sequence-templated Ag
nanocluster core (cs AgNC) is intriguing yet challenging for applicable fluorescence …

Ratiometric fluorescence biosensing of tandem biemissive Ag clusters boosted by confined catalytic DNA assembly

Y Zhang, C Yang, J He, M Li, R Yuan, W Xu - Analytical Chemistry, 2023 - ACS Publications
The reaction kinetics and yield of traditional DNA assembly with a low local concentration in
homogeneous solution remain challenging. Exploring confined catalytic DNA assembly …

Efficient intracellular MicroRNA imaging based on the localized and self-sustainable catalytic DNA assembly circuit

C Xie, R Li, X Gong, Q Zhang, Y Zhang… - Analytical …, 2023 - ACS Publications
Building dynamic biological networks, especially DNA circuits, has provided a powerful
prospect for exploring the intrinsic regulation processes of live cells. Nevertheless, for …

High-Density N-Vacancy-Induced Multipath Electrochemiluminescence Improvement of 3D gC3N4 for Ultrasensitive MiRNA-222 Analysis

W Cao, R Yuan, H Wang - Analytical Chemistry, 2023 - ACS Publications
Using dissolved O2 as the cathodic co-reactant of three-dimensional (3D) g-C3N4 is a
convenient method to improve the electrochemiluminescence (ECL) signal, but it still suffers …

Multiply guaranteed catalytic DNA circuit for cancer-cell-selective imaging of miRNA and robust evaluation of drug resistance

Z Wang, Y Shang, Y Zhu, Y He, Y Chen, X Liu… - Analytical …, 2024 - ACS Publications
Catalytic DNA circuits are desirable for sensitive bioimaging in living cells; yet, it remains a
challenge to monitor these intricate signal communications because of the uncontrolled …