In the last few decades, targeting cancer by the use of dietary phytochemicals has gained
enormous attention. The plausible reason and believe or mind set behind this fact is …

Iron plays a vital role in several cellular functions due to its unique physiochemical
properties. Iron concentration increases in the brain with age due to multiple factors …

The present study was aimed to develop silybin phytosome (SIBP) and evaluate its
effectiveness against cerebral ischemia‐reperfusion (CIR) injury in rats. Initially, SIBP was …

Silibinin exhibits antidiabetic potential by preserving the mass and function of pancreatic β-
cells through up-regulation of estrogen receptor-α (ERα) expression. However, the …

Abstract Hsp70 (heat shock protein 70) plays critical roles in cancer cell proliferation and
apoptosis. Recently, accumulating evidences have demonstrated the cancer promoting …

Heart failure (HF) is a highly morbid syndrome that seriously affects the physical and mental
health of patients and generates an enormous socio-economic burden. In addition to cardiac …

Aim Diabetic nephropathy (DN) is the leading cause of end-stage renal disease. Silibinin is
a flavonoid compound which has medicinal value. Previous studies revealed that silibinin …

Purpose: The protective effect of silibinin on kidney and lung parenchyma during hepatic
ischemia/reperfusion injury (IRI) is explored. Methods: Sixty-three Wistar rats were …

Dysregulation of histone demethylase Jumonji-C domain-containing protein 5 (JMJD5) has
been identified as a great effect on tumorigenesis. Silibinin is a commonly used anti …

Background/Aim: About 40% of patients with diffuse large cell lymphoma (DLBCL) still have
a poor prognosis. Additionally, DLBCL patients treated with doxorubicin are at risk of cardiac …