Interstitial lung diseases

M Wijsenbeek, A Suzuki, TM Maher - The Lancet, 2022 - thelancet.com
Over 200 interstitial lung diseases, from ultra rare to relatively common, are recognised.
Most interstitial lung diseases are characterised by inflammation or fibrosis within the …

Challenges of sarcoidosis and its management

M Drent, ED Crouser, J Grunewald - New England Journal of …, 2021 - Mass Medical Soc
Sarcoidosis Sarcoidosis is a lung disease of unknown cause characterized by noncaseating
granulomas; the heart and nervous system may also be involved. It is often misdiagnosed; …

[HTML][HTML] Clinical manifestations, diagnosis, and treatment of sarcoidosis

P Ungprasert, JH Ryu, EL Matteson - Mayo Clinic Proceedings: Innovations …, 2019 - Elsevier
The focus of this review is current knowledge about the epidemiology, clinical
manifestations, diagnosis, and treatment of both pulmonary sarcoidosis and extrapulmonary …

[HTML][HTML] The natural history of progressive fibrosing interstitial lung diseases

M Kolb, M Vašáková - Respiratory research, 2019 - Springer
A proportion of patients with certain types of interstitial lung disease (ILD), including chronic
hypersensitivity pneumonitis and ILDs associated with autoimmune diseases, develop a …

[HTML][HTML] Sarcoidosis: causes, diagnosis, clinical features, and treatments

R Jain, D Yadav, N Puranik, R Guleria… - Journal of Clinical …, 2020 - mdpi.com
Sarcoidosis is a multisystem granulomatous disease with nonspecific clinical manifestations
that commonly affects the pulmonary system and other organs including the eyes, skin, liver …

[HTML][HTML] The role of diverse immune cells in sarcoidosis

H Zhang, U Costabel, H Dai - Frontiers in immunology, 2021 - frontiersin.org
Sarcoidosis is a systemic inflammatory disorder of unknown etiology characterized by tissue
infiltration with macrophages and lymphocytes and associated non-caseating granuloma …

[HTML][HTML] Tofacitinib treatment and molecular analysis of cutaneous sarcoidosis

W Damsky, D Thakral, N Emeagwali… - New England Journal …, 2018 - Mass Medical Soc
There is evidence that Janus kinase (JAK)–signal transducer and activator of transcription
(STAT) signaling plays a role in the pathogenesis of sarcoidosis. We treated a patient with …

Janus kinase inhibition induces disease remission in cutaneous sarcoidosis and granuloma annulare

W Damsky, D Thakral, MK McGeary, J Leventhal… - Journal of the American …, 2020 - Elsevier
Background Sarcoidosis and granuloma annulare (GA) are cutaneous granulomatous
disorders that can be difficult to treat. There is evidence of underlying Janus kinase (JAK) …

[HTML][HTML] COVID-19 pneumonia: relationship between inflammation assessed by whole-body FDG PET/CT and short-term clinical outcome

M Dietz, G Chironi, YE Claessens, RL Farhad… - European journal of …, 2021 - Springer
Abstract Purpose [18F]-2-Fluoro-2-deoxy-D-glucose PET/CT (FDG PET/CT) is a sensitive
and quantitative technic for detecting inflammatory process. Glucose uptake is correlated …

Refractory sarcoidosis: a review

T El Jammal, Y Jamilloux… - … and clinical risk …, 2020 - Taylor & Francis
Sarcoidosis is a multi-system disease of unknown etiology characterized by granuloma
formation in various organs (especially lung and mediastinohilar lymph nodes). In more than …