Adult onset Still disease (AOSD) is a systemic inflammatory disorder characterized by skin
rash, spiking fever, arthritis, sore throat, lymphadenopathy, and hepatosplenomegaly …

Ventricular remodeling is the progressive pathologic change of the original substance and
morphology of the ventricle caused by various injuries and has attracted increasing attention …

Background Inflammation is a major contributing factor in myocardial ischemia/reperfusion
(I/R) injury, and targeting macrophage inflammation is an effective strategy for myocardial I/R …

The coronary reperfusion following acute myocardial infarction can paradoxically trigger
myocardial ischemia-reperfusion (IR) injury. This complex phenomenon involves the …

Inflammatory factors, such as the IL-1 family, are generally acknowledged to be involved in
systemic diseases and IL-1α and IL-1β, in particular, have been linked to cardiovascular …

Abstract Objectives Interleukin (IL)-38 was discovered as an anti-inflammatory factor.
However, IL-38′ s role in M1 macrophage polarization in the temporomandibular joint …

Ischemic heart disease (IHD) is a leading cause of disability and death worldwide, with
immune regulation playing a crucial role in its pathogenesis. Various immune cells are …

Abstract Interleukin (IL)‐38 is a newly discovered cytokine of the IL‐1 family, which binds
various receptors (ie, IL‐36R, IL‐1 receptor accessory protein‐like 1, and IL‐1R1) in the …

In the mammalian heart, cardiomyocytes undergo a transient window of proliferation that
leads to regenerative impairment, limiting cardiomyocyte proliferation and myocardial repair …

Inflammation is the primary pathological process of myocardial ischemia/reperfusion injury
(MI/RI). 7-Hydroxyflavone (HF), a natural flavonoid with a variety of bioactivities, plays a …