Curcumin–piperine mixtures in self-microemulsifying drug delivery system for ulcerative colitis therapy

Q Li, W Zhai, Q Jiang, R Huang, L Liu, J Dai… - International journal of …, 2015 - Elsevier
Curcumin (CUR) is a poorly water-soluble drug and its absorption is very low. In this study,
CUR and piperine (PIP) were co-encapsulated into the nanoformulation called self …

Curcumin ameliorates neuropathic pain by down-regulating spinal IL-1β via suppressing astroglial NALP1 inflammasome and JAK2-STAT3 signalling

S Liu, Q Li, MT Zhang, QL Mao-Ying, LY Hu, GC Wu… - Scientific reports, 2016 - nature.com
Curcumin has been shown to possess strong anti-inflammatory activity in many diseases. It
has been demonstrated that the janus kinase 2 (JAK2)-signal transducer and activator of …

Dietary squalene supplementation improves DSS‐induced acute colitis by downregulating p38 MAPK and NFkB signaling pathways

S Sánchez‐Fidalgo, I Villegas… - Molecular Nutrition & …, 2015 - Wiley Online Library
Scope Squalene is a polyunsaturated triterpene, which has exhibited anticancer and
antioxidant activities among others. We investigated dietary squalene supplementation …

Curcumin ameliorates autoimmune diabetes. Evidence in accelerated murine models of type 1 diabetes

CN Castro, AE Barcala Tabarrozzi… - Clinical & …, 2014 - academic.oup.com
Summary Type 1 diabetes (T1DM) is a T cell-mediated autoimmune disease that selectively
destroys pancreatic β cells. The only possible cure for T1DM is to control autoimmunity …

[HTML][HTML] Hydrogen peroxide production by lactobacilli promotes epithelial restitution during colitis

AK Singh, RY Hertzberger, UG Knaus - Redox biology, 2018 - Elsevier
Inflammatory bowel disease (IBD) is a multifactorial chronic inflammatory disease of the
gastrointestinal tract, characterized by cycles of acute flares, recovery and remission phases …

Algal oil rich in n-3 PUFA alleviates DSS-induced colitis via regulation of gut microbiota and restoration of intestinal barrier

Z Xu, H Tang, F Huang, Z Qiao, X Wang… - Frontiers in …, 2020 - frontiersin.org
Algal oil is rich in docosahexaenoic acid (DHA) and has various health benefits against
human metabolic disorders and disease. This study aimed to investigate the effects of DHA …

Polyphenols and inflammatory bowel disease: Natural products with therapeutic effects?

M Vaghari-Tabari, F Alemi, M Zokaei… - Critical Reviews in …, 2024 - Taylor & Francis
Inflammatory bowel disease (IBD) is a long-life disease with periods of recurrence and relief.
Oxidative stress plays an important role in the pathogenesis of this disease. Recent years' …

Nutraceuticals and biotics in pediatric gastrointestinal disorders

A Corsello, L Scatigno, G Fiore, S Baresi… - European Journal of …, 2024 - nature.com
In recent years there has been growing interest in the use of nutraceuticals and biotics in
both pediatric and adult clinical practice. The overlapping and often ambiguous symptoms of …

IBD: in food we trust

R Marion-Letellier, G Savoye… - Journal of Crohn's and …, 2016 - academic.oup.com
Abstract Background and Aims: Both science and patients associate diet with inflammatory
bowel disease [IBD]. There is no doubt that links between IBD and diet are numerous, based …

Curcumin improves epithelial barrier integrity of Caco‐2 monolayers by inhibiting endoplasmic reticulum stress and subsequent apoptosis

X Zhou, M Ren, J Yang, H Pan… - … Research and Practice, 2021 - Wiley Online Library
Curcumin is a natural polyphenol and is supposed to possess antioxidant, anti‐
inflammatory, anticancer, and antiapoptotic properties. Although some studies have reported …