[HTML][HTML] Effect of cofactors on NAFLD/NASH and MAFLD. A paradigm illustrating the pathomechanics of organ dysfunction

A Lonardo, AK Singal, N Osna… - Metabolism and target …, 2022 - ncbi.nlm.nih.gov
Primary nonalcoholic fatty liver disease (NAFLD) is bi-directionally associated with the
metabolic syndrome and its constitutive features (“factors”: impaired glucose disposal …

Bidirectional association between psoriasis and nonalcoholic fatty liver disease: real-world evidence from two longitudinal cohort studies

SY Gau, KH Huang, CH Lee, YH Kuan… - Frontiers in …, 2022 - frontiersin.org
Background Association between nonalcoholic fatty liver disease (NAFLD) and future
psoriasis has not yet been confirmed, although the two diseases partially share a common …

Cost-effectiveness of MRE versus VCTE in staging fibrosis for nonalcoholic fatty liver disease (NAFLD) patients with advanced fibrosis

K Sangha, ST Chang, R Cheung, VS Deshpande - Hepatology, 2023 - journals.lww.com
Methods: A Markov model was developed from the US perspective. The base-case scenario
in this model included patients aged 50 years with a Fibrosis-4 score of≥ 2.67 and …

Mori fructus aqueous extracts attenuates liver injury by inhibiting ferroptosis via the Nrf2 pathway

Y Wei, C Gao, H Wang, Y Zhang, J Gu, X Zhang… - Journal of Animal …, 2023 - Springer
Background Liver fibrosis and hepatocellular carcinogenesis secondary to liver fibrosis are
serious liver diseases with no effective treatments. Mori fructus aqueous extracts (MFAEs) …

Glycolysis in hepatic stellate cells coordinates fibrogenic extracellular vesicle release spatially to amplify liver fibrosis

S Khanal, Y Liu, AO Bamidele, AQ Wixom… - Science …, 2024 - science.org
Liver fibrosis is characterized by the activation of perivascular hepatic stellate cells (HSCs),
the release of fibrogenic nanosized extracellular vesicles (EVs), and increased HSC …

Co-treatments of gardeniae fructus and silymarin ameliorates excessive oxidative stress-driven liver fibrosis by regulation of hepatic Sirtuin1 activities using …

JA Lee, MR Shin, JW Choi, MJ Kim, HJ Park, SS Roh - Antioxidants, 2022 - mdpi.com
Gardeniae Fructus (GF, the dried ripe fruits of Gardenia jasminoides Ellis) has traditionally
been used to treat various diseases in East Asian countries, such as liver disease. Silymarin …

Quality of life in adults with metabolic dysfunction-associated fatty liver disease

TI Hwang, AL Han - International Journal of Environmental Research and …, 2021 - mdpi.com
The aims of this study were as follows: to investigate the association between metabolic
dysfunction-associated fatty liver disease (MAFLD) and health-related quality of life …

Global perspective on nonalcoholic fatty liver disease and nonalcoholic steatohepatitis‐prevalence, clinical impact, economic implications and management strategies

P Golabi, S Owrangi… - Alimentary Pharmacology …, 2024 - Wiley Online Library
Background The metabolically‐based liver disease, nonalcoholic fatty liver disease
(NAFLD), is the most common cause of chronic liver disease currently affecting 38% of the …

Development of a predictive nomogram for in-hospital death risk in multimorbid patients with hepatocellular carcinoma undergoing Palliative Locoregional Therapy

R Yao, B Zheng, X Hu, B Ma, J Zheng, K Yao - Scientific Reports, 2024 - nature.com
Patients diagnosed with hepatocellular carcinoma (HCC) often present with multimorbidity,
significantly contributing to adverse outcomes, particularly in-hospital mortality. This study …

[HTML][HTML] Disease severity predicts higher healthcare costs among hospitalized nonalcoholic fatty liver disease/nonalcoholic steatohepatitis (NAFLD/NASH) patients in …

M Romero-Gomez, N Kachru, MA Zamorano, J Darba… - Medicine, 2020 - journals.lww.com
The rising prevalence of nonalcoholic fatty liver disease (NAFLD) and nonalcoholic
steatohepatitis (NASH) presents many public health challenges, including a substantial …