Reprogramming of Treg cells in the inflammatory microenvironment during immunotherapy: a literature review

X Wu, Z Zhou, Q Cao, Y Chen, J Gong… - Frontiers in …, 2023 - frontiersin.org
Regulatory T cells (Treg), as members of CD4+ T cells, have garnered extensive attention in
the research of tumor progression. Treg cells have the function of inhibiting the immune …

Effect of external beam radiation therapy versus transcatheter arterial chemoembolization for non-diffuse hepatocellular carcinoma (≥ 5 cm): a multicenter experience …

K Su, F Wang, X Li, H Chi, J Zhang, K He… - Frontiers in …, 2023 - frontiersin.org
Background The optimal local treatment for HCC with tumor diameter≥ 5 cm is not well
established. This research evaluated the effectiveness of external beam radiation therapy …

Drug‐Eluting Shear‐Thinning Hydrogel for the Delivery of Chemo‐and Immunotherapeutic Agents for the Treatment of Hepatocellular Carcinoma

N Falcone, M Ermis, A Gangrade… - Advanced Functional …, 2024 - Wiley Online Library
Hepatocellular carcinoma (HCC) is a malignant and deadly form of liver cancer with limited
treatment options. Transcatheter arterial chemoembolization, a procedure that delivers …

Mechanism of M2 type macrophage-derived extracellular vesicles regulating PD-L1 expression via the MISP/IQGAP1 axis in hepatocellular carcinoma immunotherapy …

X Wang, X Ye, Y Chen, J Lin - International Immunopharmacology, 2023 - Elsevier
Background Hepatocellular carcinoma (HCC) is a prevailing cancer affecting human health.
M2 macrophages are essential in mediating immune responses in tumors. This study …

The multikinase inhibitor axitinib in the treatment of advanced hepatocellular carcinoma: the current clinical applications and the molecular mechanisms

H Jiang, J Liao, L Wang, C Jin, J Mo… - Frontiers in …, 2023 - frontiersin.org
Advanced hepatocellular carcinoma (HCC) is a formidable public health problem with
limited curable treatment options. Axitinib, an oral tyrosine kinase inhibitor, is a potent and …

Efficacy and safety of atezolizumab plus bevacizumab versus lenvatinib for unresectable hepatocellular carcinoma: a systematic review and meta-analysis

J Liu, L Yang, S Wei, J Li, P Yi - Journal of Cancer Research and Clinical …, 2023 - Springer
Background Atezolizumab plus bevacizumab and lenvatinib are the current first-line
systematic therapy for unresectable hepatocellular carcinoma (uHCC). However, the …

WTAP‐induced N6‐methyladenosine of PD‐L1 blocked T‐cell‐mediated antitumor activity under hypoxia in colorectal cancer

Q Liu, N Zhang, J Chen, M Zhou, D Zhou… - Cancer …, 2024 - Wiley Online Library
Abstract N 6‐Methyladenosine (m6A) is a important process regulating gene expression
post‐transcriptionally. Programmed death ligand 1 (PD‐L1) is a major immune inhibitive …

[HTML][HTML] Predictive models for response and survival in patients treated with anti-PD-1 monotherapy or with anti-PD-1 and ipilimumab combination: editorial …

A Rotte - Annals of Translational Medicine, 2023 - ncbi.nlm.nih.gov
Clinical and Regulatory Affairs, Arcellx Inc., Redwood City, CA, USA Correspondence to:
Anand Rotte. Clinical and Regulatory Affairs, Arcellx Inc., Redwood City, CA, USA. Email …

NUP43 promotes PD-L1/nPD-L1/PD-L1 feedback loop via TM4SF1/JAK/STAT3 pathway in colorectal cancer progression and metastatsis

F Wu, G Sun, Y Nai, X Shi, Y Ma, H Cao - Cell Death Discovery, 2024 - nature.com
Programmed cell death-ligand 1 (PD-L1) has a significant role in tumor progression and
metastasis, facilitating tumor cell evasion from immune surveillance. PD-L1 can be detected …

Immune-related adverse events correlate with the efficacy of PD-1 inhibitors combination therapy in advanced cholangiocarcinoma patients: A retrospective cohort …

Y Zhang, X Wang, Y Li, Y Hong, Q Zhao… - Frontiers in …, 2023 - frontiersin.org
Background Whether irAEs can predict the efficacy of PD-1 inhibitors in cholangiocarcinoma
(CCA) has not been assessed. Therefore, this study aims to investigate the correlation …