The role of immune modulatory cytokines in the tumor microenvironments of head and neck squamous cell carcinomas
N Kondoh, M Mizuno-Kamiya - Cancers, 2022 - mdpi.com
Simple Summary Malignant phenotypes of head and neck squamous cell carcinomas
(HNSCCs) are regulated by the pro-and anti-tumoral activities of immune modulatory …
(HNSCCs) are regulated by the pro-and anti-tumoral activities of immune modulatory …
Overcoming resistance to immune checkpoint inhibitors in head and neck squamous cell carcinomas
LV Dos Santos, CM Abrahão, WN William Jr - Frontiers in oncology, 2021 - frontiersin.org
Preclinical data suggest that head and neck squamous cell carcinomas (HNSCC) may
evade immune surveillance and induce immunosuppression. One mechanism of immune …
evade immune surveillance and induce immunosuppression. One mechanism of immune …
Predictive factors in the treatment of oral squamous cell carcinoma using PD-1/PD-L1 inhibitors
A Gao, X Pan, X Yang, Z Lin - Investigational new drugs, 2021 - Springer
Due to immune impairment and lymphocyte enrichment of oral squamous cell carcinoma
(OSCC), anti-PD-1/PD-L1 therapy is regarded as a potential treatment option. However …
(OSCC), anti-PD-1/PD-L1 therapy is regarded as a potential treatment option. However …
Emerging drugs for head and neck cancer
Y Wen, JR Grandis - Expert opinion on emerging drugs, 2015 - Taylor & Francis
Introduction: Despite improvements in treatment, survival rates of head and neck squamous
cell carcinoma (HNSCC) are stagnant. The existing chemotherapeutic agents are non …
cell carcinoma (HNSCC) are stagnant. The existing chemotherapeutic agents are non …
Systemic inflammation is an independent predictive marker of clinical outcomes in mucosal squamous cell carcinoma of the head and neck in oropharyngeal and non …
KA Charles, BDW Harris, CR Haddad, SJ Clarke… - BMC cancer, 2016 - Springer
Background Currently there are very few biomarkers to identify head and neck squamous
cell carcinoma (HNSCC) cancer patients at a greater risk of recurrence and shortened …
cell carcinoma (HNSCC) cancer patients at a greater risk of recurrence and shortened …
Characterization and differentiation of the tumor microenvironment (TME) of orthotopic and subcutaneously grown head and neck squamous cell carcinoma (HNSCC) …
M Brand, S Laban, MN Theodoraki, J Doescher… - International Journal of …, 2020 - mdpi.com
For the development and evaluation of new head and neck squamous cell carcinoma
(HNSCC) therapeutics, suitable, well-characterized animal models are needed. Thus, by …
(HNSCC) therapeutics, suitable, well-characterized animal models are needed. Thus, by …
Characterization of the immune profile of oral tongue squamous cell carcinomas with advancing disease
We investigated whether a unique immune response was instigated with the development of
oral tongue squamous cell carcinomas (OTSCC), with/without nodal involvement …
oral tongue squamous cell carcinomas (OTSCC), with/without nodal involvement …
Cetuximab reconstitutes pro-inflammatory cytokine secretions and tumor-infiltrating capabilities of sMICA-inhibited NK cells in HNSCC tumor spheroids
S Klöss, N Chambron, T Gardlowski, S Weil… - Frontiers in …, 2015 - frontiersin.org
Immunosuppressive factors, such as soluble major histocompatibility complex class I chain-
related peptide A (sMICA) and transforming growth factor beta 1 (TGF-β1), are involved in …
related peptide A (sMICA) and transforming growth factor beta 1 (TGF-β1), are involved in …
Systematic profiling of immune risk model to predict survival and immunotherapy response in head and neck squamous cell carcinoma
X Liu, J Chen, W Lu, Z Zeng, J Li, X Jiang, Y Gao… - Frontiers in …, 2020 - frontiersin.org
Background and Purpose Head and neck squamous carcinoma (HNSCC), characterized by
immunosuppression, is a group of highly heterogeneous cancers. Although immunotherapy …
immunosuppression, is a group of highly heterogeneous cancers. Although immunotherapy …
The immune system and head and neck squamous cell carcinoma: from carcinogenesis to new therapeutic opportunities
ME Freiser, P Serafini, DT Weed - Immunologic research, 2013 - Springer
Head and neck squamous cell carcinomas (HNSCCs) exhibit complex interactions with the
host immune system that may simultaneously explain resistance to various therapeutic …
host immune system that may simultaneously explain resistance to various therapeutic …