Laboratory models of post-traumatic stress disorder: The elusive bridge to translation

JE Dunsmoor, JM Cisler, GA Fonzo, SK Creech… - Neuron, 2022 - cell.com
Post-traumatic stress disorder (PTSD) is a debilitating mental illness composed of a
heterogeneous collection of symptom clusters. The unique nature of PTSD as arising from a …

Stress to inflammation and anhedonia: Mechanistic insights from preclinical and clinical models

CC Boyle, JE Bower, NI Eisenberger… - … & Biobehavioral Reviews, 2023 - Elsevier
Anhedonia, as evidenced by impaired pleasurable response to reward, reduced reward
motivation, and/or deficits in reward-related learning, is a common feature of depression …

[HTML][HTML] Baicalein ameliorates cerebral ischemia-reperfusion injury by inhibiting ferroptosis via regulating GPX4/ACSL4/ACSL3 axis

M Li, Z Meng, S Yu, J Li, Y Wang, W Yang… - Chemico-biological …, 2022 - Elsevier
Accumulating evidence have indicated that ferroptosis plays a crucial role in cerebral
ischemia-reperfusion (I/R) injury which is the most serious treatment complication of …

Inflammationdriven brain and gut barrier dysfunction in stress and mood disorders

E Doney, A Cadoret, L DionAlbert… - European Journal of …, 2022 - Wiley Online Library
Regulation of emotions is generally associated exclusively with the brain. However, there is
evidence that peripheral systems are also involved in mood, stress vulnerability vs …

The emerging role of the gut microbiome in posttraumatic stress disorder

S Ke, J Hartmann, KJ Ressler, YY Liu… - Brain, behavior, and …, 2023 - Elsevier
Posttraumatic stress disorder (PTSD) occurs in some people following exposure to a
terrifying or catastrophic event involving actual/threatened death, serious injury, or sexual …

Functional connectivity of the brain across rodents and humans

N Xu, TJ LaGrow, N Anumba, A Lee, X Zhang… - Frontiers in …, 2022 - frontiersin.org
Resting-state functional magnetic resonance imaging (rs-fMRI), which measures the
spontaneous fluctuations in the blood oxygen level-dependent (BOLD) signal, is …

[HTML][HTML] MDMA-assisted psychotherapy for PTSD: Growing evidence for memory effects mediating treatment efficacy

M Sarmanlu, KPC Kuypers, P Vizeli… - Progress in Neuro …, 2024 - Elsevier
The application of MDMA in conjunction with psychotherapy has in recent years seen a
resurgence of clinical, scientific, and public interest in the treatment of posttraumatic stress …

Challenges in the use of animal models and perspectives for a translational view of stress and psychopathologies

NCB Barroca, G Della Santa, D Suchecki… - Neuroscience & …, 2022 - Elsevier
The neurobiology and development of treatments for stress-related neuropsychiatric
disorders rely heavily on animal models. However, the complexity of these disorders makes …

[图书][B] Animal ethics in the wild: Wild animal suffering and intervention in nature

C Faria - 2022 - books.google.com
Animals, like humans, suffer and die from natural causes. This is particularly true of animals
living in the wild, given their high exposure to, and low capacity to cope with, harmful natural …

Regional gray matter oligodendrocyte-and myelin-related measures are associated with differential susceptibility to stress-induced behavior in rats and humans

KLP Long, LL Chao, Y Kazama, A An, KY Hu… - Translational …, 2021 - nature.com
Individual reactions to traumatic stress vary dramatically, yet the biological basis of this
variation remains poorly understood. Recent studies demonstrate the surprising plasticity of …