Current Advances in the Management of Nonurothelial Subtypes of Bladder Cancer

E Vlachou, BA Johnson III, E Baraban… - American Society of …, 2024 - ascopubs.org
Urothelial cancer (UC) is the most common histology seen in bladder tumors. The 2022
WHO classification of urinary tract tumors includes a list of less common subtypes (formerly …

Bladder cancer variants—one disease with many faces

B Czerniak - Nature Reviews Urology, 2024 - nature.com
Bladder cancer progression to microscopically distinct variants such as sarcomatoid, small
cell, micropapillary and plasmacytoid is associated with more aggressive clinical behaviour …

Integrated immuno-transcriptomic analysis of ovarian cancer identifies a four-chemokine-dominated subtype with antitumor immune-active phenotype and favorable …

L Zhuo, F Meng, K Sun, M Zhou, J Sun - British Journal of Cancer, 2024 - nature.com
Background Ovarian cancer (OV) is a heterogeneous disease but has traditionally been
treated as an immunologically cold malignancy. The relationship between the immune …

Differential NEUROD1, ASCL1, and POU2F3 Expression Defines Molecular Subsets of Bladder Small Cell/Neuroendocrine Carcinoma with Prognostic Implications

D Akbulut, K Whiting, MY Teo, JE Tallman, GG Ozcan… - Modern Pathology, 2024 - Elsevier
Small cell carcinomas (SMC) of the lung are now molecularly classified based on the
expression of transcriptional regulators (NEUROD1, ASCL1, POU2F3, and YAP1) and …

Plasmacytoid urothelial carcinoma of the urinary bladder–A clinicopathological and molecular analysis of 52 cases

L Zheng, H Chen, J Zhao, S Roy-Chowdhuri… - Human Pathology, 2024 - Elsevier
Plasmacytoid urothelial carcinoma (UC) is a rare histologic subtype of bladder cancer that is
associated with an aggressive clinical behavior. We analyzed the clinicopathologic and …

[HTML][HTML] Integrated bioinformatics investigation of adenylyl cyclase family co-expression network in bladder cancer followed by preliminary validation of member 2 …

H Wang, W Luo, J Ji, M Qu, S Jiang… - Translational Cancer …, 2024 - ncbi.nlm.nih.gov
Background The adenylyl cyclase (ADCY) gene family encodes enzymes responsible for the
synthesis of cyclic adenosine monophosphate (cAMP) from adenosine triphosphate (ATP) …

Histologic variants in bladder cancer harbor aggressive molecular features including TM4SF1 expression and a CA125+ cell state

H Yang, H Song, E Yip, K Chang, P Allegakoen, KL Lu… - bioRxiv, 2024 - biorxiv.org
Histologic variant (HV) subtypes of bladder cancer are clinically aggressive tumors that are
more resistant to standard therapy compared to conventional urothelial carcinoma (UC) …