Photosensitization reactions of biomolecules: definition, targets and mechanisms

MS Baptista, J Cadet, A Greer… - Photochemistry and …, 2021 - Wiley Online Library
Photosensitization reactions have been demonstrated to be largely responsible for the
deleterious biological effects of UV and visible radiation, as well as for the curative actions of …

Technological advances towards extracellular vesicles mass production

A Grangier, J Branchu, J Volatron, M Piffoux… - Advanced Drug Delivery …, 2021 - Elsevier
Extracellular vesicles (EVs) are becoming essential actors in bio-therapeutics, as much for
their regenerative or immunomodulatory properties as for their potential as cargo delivery …

Oncolysis without viruses—inducing systemic anticancer immune responses with local therapies

O Kepp, A Marabelle, L Zitvogel… - Nature Reviews Clinical …, 2020 - nature.com
Local administration of oncolytic viruses to tumours can promote anticancer immune
responses that lead to the abscopal regression of distant metastases, especially in patients …

Insight on pyrimido [5, 4-g] indolizine and pyrimido [4, 5-c] pyrrolo [1, 2-a] azepine systems as promising photosensitizers on malignant cells

M Barreca, AM Ingarra, MV Raimondi, V Spanò… - European Journal of …, 2022 - Elsevier
Searching for new small molecules as photosensitizing agents, we have developed a class
of twenty-five pyrimido [5, 4-g] indolizine and pyrimido [4, 5-c] pyrrolo [1, 2-a] azepines with a …

The immunopathogenesis and immunotherapy of cutaneous T cell lymphoma: Current and future approaches

DM Weiner, JS Durgin, M Wysocka, AH Rook - Journal of the American …, 2021 - Elsevier
In the past few decades, immunotherapy has emerged as an effective therapeutic option for
patients with cutaneous T cell lymphoma (CTCL). CTCL is characterized by progressive …

Lymphocyte depleting and modulating therapies for chronic lung allograft dysfunction

S Bos, P Pradère, H Beeckmans, A Zajacova… - Pharmacological …, 2023 - ASPET
Chronic lung rejection, also called chronic lung allograft dysfunction (CLAD), remains the
major hurdle limiting long-term survival after lung transplantation, and limited therapeutic …

Extracorporeal photopheresis: a case of immunotherapy ahead of its time

PA Vieyra-Garcia, P Wolf - Transfusion Medicine and Hemotherapy, 2020 - karger.com
Extracorporeal photopheresis (ECP) is a cell-based immunotherapy that involves the
reinfusion of autologous leukocytes after exposure to psoralen and UVA. The treatment has …

Noninfectious pulmonary complications of haematopoietic stem cell transplantation

S Haider, N Durairajan… - European Respiratory …, 2020 - Eur Respiratory Soc
Haematopoietic stem cell transplantation (HSCT) is an established treatment for a variety of
malignant and nonmalignant conditions. Pulmonary complications, both infectious and …

[HTML][HTML] Pathogenesis and therapy of primary cutaneous T-cell lymphoma: Collegium Internationale Allergologicum (CIA) update 2020

M Bobrowicz, C Fassnacht, D Ignatova… - International archives of …, 2020 - karger.com
Cutaneous T-cell lymphoma (CTCL) is a heterogeneous disease group of unknown etiology
with a complex immunological background. As CTCL arises from T cells that have a vital role …

Application of photodynamic therapy in immune-related diseases

D Yang, S Lei, K Pan, T Chen, J Lin, G Ni, J Liu… - Photodiagnosis and …, 2021 - Elsevier
Photodynamic therapy (PDT) is a therapeutic modality that utilizes photodamage caused by
photosensitizers and oxygen after exposure to a specific wavelength of light. Owing to its low …