[HTML][HTML] Immunoinformatics Design of Multi-Epitope Peptide-Based Vaccine Against Schistosoma mansoni Using Transmembrane Proteins as a Target

RCO Sanches, S Tiwari, LCG Ferreira… - Frontiers in …, 2021 - frontiersin.org
Schistosomiasis remains a serious health issue nowadays for an estimated one billion
people in 79 countries around the world. Great efforts have been made to identify good …

Translational informatics for human microbiota: data resources, models and applications

K Shen, AU Din, B Sinha, Y Zhou… - Briefings in …, 2023 - academic.oup.com
With the rapid development of human intestinal microbiology and diverse microbiome-
related studies and investigations, a large amount of data have been generated and …

[HTML][HTML] Immunoinformatics analysis of sars-cov-2 orf1ab polyproteins to identify promiscuous and highly conserved t-cell epitopes to formulate vaccine for indonesia …

M Gustiananda, BP Sulistyo, D Agustriawan, S Andarini - Vaccines, 2021 - mdpi.com
SARS-CoV-2 and its variants caused the COVID-19 pandemic. Vaccines that target
conserved regions of SARS-CoV-2 and stimulate protective T-cell responses are important …

Design of multi-epitope based vaccine against Mycobacterium tuberculosis: a subtractive proteomics and reverse vaccinology based immunoinformatics approach

SS Nayak, G Sethi, K Ramadas - Journal of Biomolecular Structure …, 2023 - Taylor & Francis
Tuberculosis is an airborne transmissible disease caused by Mycobacterium tuberculosis
that infects millions of lives worldwide. There is still no single comprehensive therapy or …

An AedesAnopheles Vaccine Candidate Supplemented with BCG Epitopes Against the Aedes and Anopheles Genera to Overcome Hypersensitivity to Mosquito …

M Naveed, U Ali, T Aziz, R Naveed, S Mahmood… - Acta Parasitologica, 2024 - Springer
Background Skeeter syndrome is a severe local allergic response to mosquito bites that is
accompanied by considerable inflammation and, in some cases, a systemic response like …

[HTML][HTML] Network-Based Metabolism-Centered Screening of Potential Drug Targets in Klebsiella pneumoniae at Genome Scale

MF Cesur, B Siraj, R Uddin, S Durmuş… - Frontiers in cellular and …, 2020 - frontiersin.org
Klebsiella pneumoniae is an opportunistic bacterial pathogen leading to life-threatening
nosocomial infections. Emergence of highly resistant strains poses a major challenge in the …

[HTML][HTML] In Silico Designed Multi-Epitope Immunogen “Tpme-VAC/LGCM-2022” May Induce Both Cellular and Humoral Immunity against Treponema pallidum …

LGR Gomes, TCV Rodrigues, AK Jaiswal, RG Santos… - Vaccines, 2022 - mdpi.com
Syphilis, a sexually transmitted infection caused by the spirochete Treponema pallidum, has
seen a resurgence over the past years. T. pallidum is capable of early dissemination and …

[HTML][HTML] Prioritization of potential drug targets and antigenic vaccine candidates against Klebsiella aerogenes using the computational subtractive proteome-driven …

V Chakkyarath, A Shanmugam, J Natarajan - Journal of Proteins and …, 2021 - Springer
Klebsiella aerogenes is a multidrug-resistant Gram-negative bacterium that causes
nosocomial infections. The organism showed resistance to most of the conventional …

PBITV3: A robust and comprehensive tool for screening pathogenic proteomes for drug targets and prioritizing vaccine candidates

S Chakraborty, M Askari, RS Barai… - Protein …, 2024 - Wiley Online Library
Rise of life‐threatening superbugs, pandemics and epidemics warrants the need for cost‐
effective and novel pharmacological interventions. Availability of publicly available …

[HTML][HTML] Enhancing explainable SARS-CoV-2 vaccine development leveraging bee colony optimised Bi-LSTM, Bi-GRU models and bioinformatic analysis

DU Ozsahin, ZS Ameen, AS Hassan, AS Mubarak - Scientific Reports, 2024 - nature.com
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a single-stranded
RNA virus that caused the outbreak of the coronavirus disease 2019 (COVID-19). The …