Thermoregulation in laboratory mammals and humans exposed to anticholinesterase agents

CJ Gordon - Neurotoxicology and teratology, 1994 - Elsevier
The regulation of body temperature is one of many homeostatic functions affected by
exposure to anticholinesterase (antiChE) pesticides, and related compounds. In the study of …

Appraisal of risks from nonoccupational exposure to chlorpyrifos

RC Cochran - Regulatory Toxicology and Pharmacology, 2002 - Elsevier
The toxicological database for chlorpyrifos indicates that humans are not more sensitive
than laboratory animals to the toxic effects. Although an oral dose of 1 mg/kg-day resulted in …

Comparative developmental and maternal neurotoxicity following acute gestational exposure to chlorpyrifos in rats

SM Chanda, P Harp, J Liu, CN Pope - Journal of Toxicology and …, 1995 - Taylor & Francis
Chlorpyrifos (CPF), an organophosphorus (OP) insecticide, exerts toxicity through inhibition
of acetylcholinesterase (AChE). In the present study, pregnant Sprague‐Dawley rats were …

[PDF][PDF] Repeated inhibition of cholinesterase by chlorpyrifos in rats: behavioral, neurochemical and pharmacological indices of tolerance.

PJ Bushnell, KL Kelly, TR Ward - Journal of Pharmacology and …, 1994 - Citeseer
Previous work from this laboratory showed that daily sc in jections of the organophosphate
diisopropylfluorophosphate caused prolonged inhibition of Cholinesterase (ChE) activity in …

Hypothermia and fever after organophosphorus poisoning in humans—a prospective case series

A Moffatt, F Mohammed, M Eddleston, S Azher… - Journal of medical …, 2010 - Springer
There have been many animal studies on the effects of organophosphorus pesticide (OP)
poisoning on thermoregulation with inconsistent results. There have been no prospective …

Effects of sublethal fenitrothion ingestion on cholinesterase inhibition, standard metabolism, thermal preference, and prey‐capture ability in the Australian central …

D Bain, WA Buttemer, L Astheimer… - … and Chemistry: An …, 2004 - Wiley Online Library
The central bearded dragon (Pogona vitticeps) is a medium‐sized lizard that is common in
semiarid habitats in Australia and that potentially is at risk of fenitrothion exposure from use …

Neuroreflex control of cardiovascular function is impaired after acute poisoning with chlorpyrifos, an organophosphorus insecticide: possible short and long term …

AF Cunha, ISA Felippe, NC Ferreira-Junior… - Toxicology, 2018 - Elsevier
Although it is well-established that severe poisoning by organophosphorus (OP) compounds
strongly affects the cardiorespiratory system, the effects of sub-lethal exposure to these …

Effect of central and peripheral cholinergic antagonists on chlorpyrifos-induced changes in body temperature in the rat

CJ Gordon, TA Grantham - Toxicology, 1999 - Elsevier
Exposure to the organophosphate (OP)-based pesticide chlorpyrifos (CHP) in the rat results
in an initial period of hypothermia lasting< 24 h, followed by a fever lasting 48–72 h. The …

Thermoregulatory aspects of environmental exposure to anticholinesterase agents

CJ Gordon - Reviews on environmental health, 1996 - degruyter.com
Anticholinesterase (antiChE) agents can be highly toxic to birds and mammals and
constitute a major proportion of the pesticides used throughout the world. AntiChEs consist …

Chlorpyrifos: lack of cognitive effects in adult Long–Evans rats

JPJ Maurissen, MR Shankar, JL Mattsson - Neurotoxicology and teratology, 2000 - Elsevier
Female Long–Evans rats were gavaged 5 days a week for 4 weeks with chlorpyrifos in oil at
dosages of 0, 1, 3, and 10 mg/kg/day. Clinical observations were conducted, and memory …