The first edition of the clinical practice guidelines for liver cirrhosis was published in 2010,
and the second edition was published in 2015 by the Japanese Society of Gastroenterology …

Accumulating evidence supports that gut dysbiosis may relate to various liver diseases.
Alcoholics with high intestinal permeability had a decrease in the abundance of …

Background We aimed to elucidate the relationship between serum myostatin levels and
other markers including skeletal muscle mass and to investigate the influence of serum …

Background Ocular changes are traditionally associated with only a few hepatobiliary
diseases. These changes are non-specific and have a low detection rate, limiting their …

Exosomal microRNAs (exo-miRs) have been promising cancer biomarkers. MiRs in
hepatocellular carcinoma (HCC) cell-derived exosomes (HEX) were analyzed to identify …

Aim Sarcopenia has a high prevalence and can be an adverse predictor in patients with
chronic liver diseases (CLDs). We sought to assess the prevalence of sarcopenia and its …

Background Cirrhosis is the outcome of chronic liver disease of any etiology due to
progressive liver injury and fibrosis. Consequently, cirrhosis leads to portal hypertension …

Aim Handgrip strength (HGS) is a marker of sarcopenia and has been used to stratify an
individual's risk of death. We aimed to assess the prognostic significance of HGS in patients …

Nonalcoholic fatty liver disease (NAFLD) is the most common cause of chronic liver
diseases worldwide, including in Japan. The Japanese Society of Gastroenterology (JSGE) …

Skeletal muscle is the largest organ in the body, and skeletal muscle atrophy results from a
shift in the balance of protein synthesis and degradation toward protein breakdown. Primary …