Measuring chondrocyte viability of articular cartilage based on label-free two-photon microscopy and deep learning image analysis

H Fan, P Xu, X Chen, Y Li, J Hsu, M Le, Z Zhang, E Ye… - bioRxiv, 2023 - biorxiv.org
Objective Chondrocyte viability (CV) is an important indicator of articular cartilage health.
Two-photon excitation autofluorescence (TPAF) and second harmonic generation (SHG) …

[PDF][PDF] Quantification methods and applications of polarization-sensitive optical coherence tomography

X Zhou - 2023 - open.library.ubc.ca
Optical coherence tomography (OCT) provides non-invasive, three-dimensional imaging of
biological tissues using back-scattered light. Since the invention of OCT technique, OCT has …

Nonlinear Microscopy System and Protocol for Rapid Evaluation of Freshly Excised Human Tissue

T Yoshitake - 2022 - dspace.mit.edu
Histopathology determines disease type/condition by microscopic evaluation of biopsy and
surgically excised tissue, playing a critical role in medicine. The clinical protocol for histology …

Nonlinear Optical Microscopy Assessment of Tissue Structure and Chondrocyte Viability of Articular Cartilage

M Le - 2022 - tigerprints.clemson.edu
Articular cartilage functions to protect the ends of bones by providing a surface that can
withstand compressive forces and minimize friction during movement. Collagen fibers form …

[PDF][PDF] Three-Dimensional Measurement of Chondrocyte Viability of Articular Cartilage Using Label-Free Imaging and Deep Learning Image Analysis

MS Hongming Fan, M Lutas, MS Zhao Zhang… - ors.org
METHODS: Cartilage samples were harvested from pig knee joints from a local butcher
shop. Each sample was stored in DPBS (Dulbecco's Phosphate-Buffered Saline, Corning) at …

Functional Imaging with Nonlinear Optical Microscopy

Y Li - 2020 - search.proquest.com
Nonlinear optical microscopy is a powerful tool for biological imaging. Using multiphoton
excitation fluorescence or second harmonic generation (SHG) as the imaging contrast …