Advances in immune checkpoint inhibitors for advanced hepatocellular carcinoma

Y Chen, H Hu, X Yuan, X Fan, C Zhang - Frontiers in immunology, 2022 - frontiersin.org
Hepatocellular carcinoma (HCC) is usually diagnosed in an advanced stage and has
become the second deadliest type of cancer worldwide. The systemic treatment of advanced …

Hepatocellular carcinoma: signaling pathways, targeted therapy, and immunotherapy

X Luo, X He, X Zhang, X Zhao, Y Zhang, Y Shi… - MedComm, 2024 - Wiley Online Library
Hepatocellular carcinoma (HCC) is the most common primary liver cancer with a high
mortality rate. It is regarded as a significant public health issue because of its complicated …

Immunotherapy as a neoadjuvant therapy for a patient with hepatocellular carcinoma in the pretransplant setting: a case report

M Abdelrahim, A Esmail, G Umoru, K Westhart… - Current …, 2022 - mdpi.com
Systemic combination therapy of immune checkpoint inhibitors and vascular endothelial
growth factors have provided the basis for improved outcomes in select patients with …

Transplant oncology: An emerging discipline of cancer treatment

M Abdelrahim, A Esmail, A Abudayyeh, N Murakami… - Cancers, 2023 - mdpi.com
Simple Summary Transplant oncology is an evolving treatment ideal for patients suffering
from various cancers with poor prognoses. The concept essentially is the complete removal …

Newest therapies for cholangiocarcinoma: an updated overview of approved treatments with transplant oncology vision

Y Zhang, A Esmail, V Mazzaferro, M Abdelrahim - Cancers, 2022 - mdpi.com
Simple Summary Cholangiocarcinoma is a relatively rare but deadly disease with
traditionally limited treatment options. The disease can be categorized by anatomic location …

[HTML][HTML] When immunotherapy meets liver transplantation for hepatocellular carcinoma: a bumpy but promising road

Y Gu, S Xu, Z Wang, J Yang, S Zheng… - Chinese Journal of …, 2023 - ncbi.nlm.nih.gov
Liver transplantation (LT) is a highly curative therapy for patients with hepatocellular
carcinoma (HCC). However, due to the shortage of donor livers and rapid progression of …

Timeline of FDA-approved targeted therapy for cholangiocarcinoma

SM Cho, A Esmail, A Raza, S Dacha, M Abdelrahim - Cancers, 2022 - mdpi.com
Simple Summary Cholangiocarcinoma constitutes around 3% of gastrointestinal cancers,
and mortality from this cancer has been rising in the recent decades. Many cases of …

Gemcitabine and cisplatin as neo-adjuvant for cholangiocarcinoma patients prior to liver transplantation: case-series

M Abdelrahim, H Al-Rawi, A Esmail, J Xu, G Umoru… - Current …, 2022 - mdpi.com
Background: The management of cholangiocarcinoma is continually reviewed on a current
evidence basis to develop practice guidelines and consensus statements. However, the …

Immune checkpoint inhibitors for solid tumors in the adjuvant setting: current progress, future directions, and role in transplant oncology

K Abboud, G Umoru, A Esmail, A Abudayyeh… - Cancers, 2023 - mdpi.com
Simple Summary Immune checkpoint inhibitors (ICIs) are being increasingly used after
primary treatment of early-stage tumors to treat any residual disease and prevent …

Immunotherapy for hepatocellular carcinoma in the setting of liver transplantation: A review

Z Lominadze, K Hill, MR Shaik, JP Canakis… - International Journal of …, 2023 - mdpi.com
The emerging field of immuno-oncology has brought exciting developments in the treatment
of hepatocellular carcinoma (HCC). It has also raised urgent questions about the role of …