DPP4 and ACE2 in diabetes and COVID-19: therapeutic targets for cardiovascular complications?
I Valencia, C Peiro, O Lorenzo… - Frontiers in …, 2020 - frontiersin.org
COVID-19 outbreak, caused by severe acute respiratory syndrome (SARS)-CoV-2
coronavirus has become an urgent health and economic challenge. Diabetes is a risk factor …
coronavirus has become an urgent health and economic challenge. Diabetes is a risk factor …
Glucose‐dependent insulinotropic polypeptide and glucagon‐like peptide‐1: incretin actions beyond the pancreas
Y Seino, D Yabe - Journal of diabetes investigation, 2013 - Wiley Online Library
Glucose‐dependent insulinotropic polypeptide (GIP) and glucagon‐like peptide‐1 (GLP‐1)
are the two primary incretin hormones secreted from the intestine on ingestion of various …
are the two primary incretin hormones secreted from the intestine on ingestion of various …
Glucocorticoids and fatty acid metabolism in humans: fuelling fat redistribution in the metabolic syndrome
DP Macfarlane, S Forbes… - Journal of …, 2008 - joe.bioscientifica.com
Estrogen affects proliferation and migration of different skin components, thus influencing
wound healing processes. The human keratinocyte cell line NCTC 2544 has been used to …
wound healing processes. The human keratinocyte cell line NCTC 2544 has been used to …
Neuroprotective effects of vildagliptin in rat rotenone Parkinson's disease model: role of RAGE‐NF κB and Nrf2‐antioxidant signaling pathways
RM Abdelsalam, MM Safar - Journal of neurochemistry, 2015 - Wiley Online Library
Gliptins have been recently shown to conquer neuronal degeneration in cell cultures via
modulating glucagon‐like peptide (GLP)‐1. This peptide produced in the gut not only …
modulating glucagon‐like peptide (GLP)‐1. This peptide produced in the gut not only …
The effects of dipeptidyl peptidase-4 inhibition on microvascular diabetes complications
A Avogaro, GP Fadini - Diabetes care, 2014 - Am Diabetes Assoc
We performed a review of the literature to determine whether the dipeptidyl peptidase-4
inhibitors (DPP4-I) may have the capability to directly and positively influence diabetic …
inhibitors (DPP4-I) may have the capability to directly and positively influence diabetic …
Crosstalk between advanced glycation end products (AGEs)-receptor RAGE axis and dipeptidyl peptidase-4-incretin system in diabetic vascular complications
S Yamagishi, K Fukami, T Matsui - Cardiovascular Diabetology, 2015 - Springer
Advanced glycation end products (AGEs) consist of heterogenous group of macroprotein
derivatives, which are formed by non-enzymatic reaction between reducing sugars and …
derivatives, which are formed by non-enzymatic reaction between reducing sugars and …
Exploring the effects of DPP-4 inhibitors on the kidney from the bench to clinical trials
Abstract Dipeptidyl-peptidase-4 (DPP-4) inhibitors are a relatively new class of non-insulin
glucose-lowering agents, belonging to the incretin family, which are able to improve …
glucose-lowering agents, belonging to the incretin family, which are able to improve …
Linagliptin blocks renal damage in type 1 diabetic rats by suppressing advanced glycation end products-receptor axis
S Nakashima, T Matsui, M Takeuchi… - Hormone and …, 2014 - thieme-connect.com
Advanced glycation end products (AGEs) and their receptor (RAGE) play a role in diabetic
nephropathy. We have recently found that linagliptin, an inhibitor of dipeptidyl peptidase-4 …
nephropathy. We have recently found that linagliptin, an inhibitor of dipeptidyl peptidase-4 …
Platelet effects of anti-diabetic therapies: new perspectives in the management of patients with diabetes and cardiovascular disease
A Nusca, D Tuccinardi, S Pieralice… - Frontiers in …, 2021 - frontiersin.org
In type 2 diabetes, anti-thrombotic management is challenging, and current anti-platelet
agents have demonstrated reduced efficacy. Old and new anti-diabetic drugs exhibited …
agents have demonstrated reduced efficacy. Old and new anti-diabetic drugs exhibited …
Vildagliptin: a review of its use in type 2 diabetes mellitus
GM Keating - Drugs, 2014 - Springer
The dipeptidyl peptidase-4 inhibitor vildagliptin (Galvus®) is approved for use as
monotherapy and combination therapy in type 2 diabetes mellitus. A fixed-dose combination …
monotherapy and combination therapy in type 2 diabetes mellitus. A fixed-dose combination …