Background Whether gastroesophageal reflux (GER) or GER disease (GERD) causes
chronic cough in children is controversial. Using the Population, Intervention, Comparison …

Proton pump inhibitors (PPI) and histamine-2 receptor antagonists (H2RA) are commonly
used medications in neonates and infants for the treatment of gastroesophageal reflux …

Objectives To perform systematic review and quantitative analysis of the literature on the
association between gastro-oesophageal reflux disease (GERD) and dental erosion in …

Importance The scope of low-value care in children's hospitals is poorly understood.
Objective To develop and apply a calculator of hospital-based pediatric low-value care to …

Objective To review the signs and symptoms of feeding difficulties in children with non–IgE-
mediated food allergic gastrointestinal disorders and provide practical advice, with the goal …

Assessment of asthma comorbidities, conditions that adversely affect the pathobiology of
asthma or impair its response to therapies, is a fundamental step in the evaluation and …

Proton pump inhibitors (PPIs) have been available for over three decades and are among
the most commonly prescribed medications. They are effective in treating a variety of gastric …

Domperidone is a peripheral dopamine-2 receptor antagonist with prokinetic and antiemetic
properties. Its prokinetic effects are mainly manifest in the upper gastrointestinal (GI) tract …

Dietary factors may play an important role in the generation of symptoms in children with
disorders of gut-brain interaction (DGBIs). Although dietary modification may provide …

Importance Eosinophilic esophagitis (EoE), a chronic disease with significant patient and
health care burden, has increased rapidly in incidence across many countries. Elucidating …