5-HT2 receptors are G-protein coupled receptors that currently comprise threesubtypes: 5-
HT2A, 5-HT2B and 5-HT2C receptors. The subtypes are related in theirmolecular structure …

The frontal cortex (FCX) plays a key role in processes that control mood, cognition and motor
behaviour, functions which are compromised in depression, schizophrenia and other …

Activation of brown adipose tissue (BAT) in humans is a strategy to treat obesity and
metabolic disease. Here we show that the serotonin transporter (SERT), encoded by …

Tissue homeostasis requires an effective, limited wound-healing response to injury. In
chronic disease, failure to regenerate parenchymal tissue leads to the replacement of lost …

The present study evaluated, via a combined electrophysiological and dialysis approach,
the potential influence of serotonin (5‐HT) 2C as compared to 5‐HT2A and 5‐HT2B …

Puberty is associated with transient insulin resistance that normally recedes at the end of
puberty; however, in overweight children, insulin resistance persists, leading to an increased …

A series of potent, selective 5HT2B receptor antagonists has been identified based upon
yohimbine, with SAR studies resulting in a 1000-fold increase in 5HT2B receptor affinity …

We recently reported the cloning of a new member of the serotonin 5‐HT2 family, the 5‐
HT2B receptor. We now report the production and characterisation of a specific antiserum …

Transforming growth factor-β1 (TGF-β1) induces myofibroblast activation of quiescent aortic
valve interstitial cells (AVICs), a differentiation process implicated in calcific aortic valve …

The exact physiological role for the monoamine serotonin (5‐HT) in modulation of insulin
secretion is yet to be fully understood. Although the presence of this monoamine in islets of …