Direct Oral Anticoagulants: Navigating Through Clinical Challenges
M Ioannou, E Leonidou, I Chaziri… - Cardiovascular Drugs and …, 2023 - Springer
Abstract Purpose Direct oral anticoagulants (DOACs) have been approved, for over a
decade, by both European and American medicine agencies, for treatment and prevention …
decade, by both European and American medicine agencies, for treatment and prevention …
Direct oral anticoagulants versus warfarin in nonvalvular atrial fibrillation patients with prior gastrointestinal bleeding: a network meta-analysis of real-world data
W Hu, H Cai, J Zhang - European Journal of Clinical Pharmacology, 2022 - Springer
Purpose The objective of present study was to compare the safety and efficacy of resuming
direct-acting oral anticoagulants (DOACs) and vitamin K antagonists (VKAs) in patients with …
direct-acting oral anticoagulants (DOACs) and vitamin K antagonists (VKAs) in patients with …
Evaluation of Apixaban safety and effectiveness in morbidly obese patients with atrial fibrillation: a retrospective cohort study
Background The benefit of apixaban to reduce stroke risk in morbidly obese patients with
nonvalvular atrial fibrillation (AF) is still undetermined. The International Society of …
nonvalvular atrial fibrillation (AF) is still undetermined. The International Society of …
Impact of Obesity on Atrial Fibrillation Pathogenesis and Treatment Options
R Sha, O Baines, A Hayes, K Tompkins… - Journal of the …, 2024 - Am Heart Assoc
Atrial fibrillation (AF) is the most common cardiac arrhythmia. AF increases the risk of stroke,
heart failure, dementia, and hospitalization. Obesity significantly increases AF risk, both …
heart failure, dementia, and hospitalization. Obesity significantly increases AF risk, both …
Single versus dual antiplatelet therapy following left atrial appendage occlusion in patients with high bleeding risk
Our study aims to compare the utility of single antiplatelet therapy (SAPT) with dual
antiplatelet therapy (DAPT) following Left atrial appendage occlusion in patients whose post …
antiplatelet therapy (DAPT) following Left atrial appendage occlusion in patients whose post …
Therapeutic Drug Monitoring of Direct Oral Anticoagulants in Patients with Extremely Low and High Body Weight—Pilot Study
Ł Wołowiec, M Kusiak, J Budzyński… - Journal of Clinical …, 2023 - mdpi.com
Phase III clinical trials for individual direct oral anticoagulants (DOACs) contained a limited
representation of subjects with abnormal body weight, which were mostly limited to a BMI> …
representation of subjects with abnormal body weight, which were mostly limited to a BMI> …
Comparing the clinical outcomes observed with rivaroxaban versus warfarin for the management of obese patients with non-valvular atrial fibrillation: a systematic …
X Zhuo, J Wang, L Shao - Cardiovascular Drugs and Therapy, 2024 - Springer
Background Atrial fibrillation (AF) is an irregular heart rhythm which is becoming more and
more common in this new era. Obesity is a risk factor for cardiovascular events, and obese …
more common in this new era. Obesity is a risk factor for cardiovascular events, and obese …
Factor Xa Inhibitors versus warfarin in patients with morbid obesity and atrial fibrillation
P Dobry, K McGrew, I Yun, R Heath, A Shafqat… - European Journal of …, 2024 - Springer
Purpose Factor Xa Inhibitors have emerged as a first-line agent in the management of non-
valvular atrial fibrillation (NVAF), but there is a need for additional data surrounding their use …
valvular atrial fibrillation (NVAF), but there is a need for additional data surrounding their use …
Safety and efficacy of direct oral anticoagulants in comparison to warfarin in obese patients with atrial fibrillation: A systematic review and meta‐analysis
A Adelkhanova, PR Oli, DB Shrestha… - Health Science …, 2024 - Wiley Online Library
Abstract Background and Aim Obesity affects nearly 650 million adults worldwide, and the
prevalence is steadily rising. This condition has significant adverse effects on cardiovascular …
prevalence is steadily rising. This condition has significant adverse effects on cardiovascular …
[PDF][PDF] The Effectiveness and Safety of Direct Oral Anticoagulants in Obese Patients With Atrial Fibrillation: A Network Meta-Analysis
QM Salah, S Bhandari, A Chand, S Khan, SHA Tirmzi… - Cureus, 2023 - cureus.com
Atrial fibrillation (AF) is a cardiac condition characterized by an irregular heart rhythm, which
is increasingly prevalent in the modern era. All international guidelines strongly advise the …
is increasingly prevalent in the modern era. All international guidelines strongly advise the …