In this second part of a 2-part series on the global burden of cardiovascular disease, we
review the proven, effective approaches to the prevention and treatment of cardiovascular …

Ischemic stroke in patients with atrial fibrillation is associated with substantial morbidity and
mortality. The growing epidemic of atrial fibrillation worldwide has raised concerns about the …

Objectives This study aimed to systematically review the use of cost-effectiveness (CE)
threshold for evaluating pharmacological interventions in Greece. Methods A systematic …

Objectives To assess cost-effectiveness of direct oral anticoagulants (DOACs) compared
with vitamin K antagonists (VKAs) for stroke prevention in atrial fibrillation (AF) by pooling …

Introduction Atrial fibrillation (AF) is associated with an increased risk of thromboembolic
events. Objectives This study compared the long-term efficacy and safety of apixaban with …

Background: Several studies have shown the cost-effectiveness of direct oral anticoagulants
(DOACs), compared with warfarin, to prevent atrial fibrillation (AF) related complications …

Background Atrial fibrillation (AF) is a severe epidemiological and public health concern
among the elderly population worldwide, with substantial economic and social burdens …

Background Warfarin use for stroke prevention in atrial fibrillation (AF) patients with chronic
kidney disease is debated. Apixaban was shown to be safer than warfarin, with superior …

Objectives Several studies have evaluated the economic evaluation of a group of
medications known as novel oral anticoagulant drugs (NOACs) in recent years. The aim of …

Our aim was to compare adverse drug reactions (ADRs) associated with direct-acting oral
anticoagulants and vitamin K antagonists from the European EudraVigilance (EV) database …