Goods and bads of the endocannabinoid system as a therapeutic target: Lessons learned after 30 years

M Maccarrone, V Di Marzo, J Gertsch, U Grether… - Pharmacological …, 2023 - ASPET
The cannabis derivative marijuana is the most widely used recreational drug in the Western
world and is consumed by an estimated 83 million individuals (∼ 3% of the world …

[HTML][HTML] Lower-Risk Cannabis Use Guidelines (LRCUG) for reducing health harms from non-medical cannabis use: A comprehensive evidence and recommendations …

B Fischer, T Robinson, C Bullen, V Curran… - International Journal of …, 2022 - Elsevier
Background Cannabis use is common, especially among young people, and is associated
with risks for various health harms. Some jurisdictions have recently moved to …

[HTML][HTML] Broad-spectrum cannabis oil ameliorates reserpine-induced fibromyalgia model in mice

EG Ferrarini, RS Paes, GM Baldasso… - Biomedicine & …, 2022 - Elsevier
Fibromyalgia (FM) is an idiopathic disorder characterized by generalized pain and
associated symptoms such as depression and anxiety. Cannabis sativa shows different …

A guide to targeting the endocannabinoid system in drug design

A Stasiulewicz, K Znajdek, M Grudzień… - International journal of …, 2020 - mdpi.com
The endocannabinoid system (ECS) is one of the most crucial systems in the human
organism, exhibiting multi-purpose regulatory character. It is engaged in a vast array of …

Management of pharmaceutical and recreational drug poisoning

B Mégarbane, M Oberlin, JC Alvarez, F Balen… - Annals of intensive …, 2020 - Springer
Background Poisoning is one of the leading causes of admission to the emergency
department and intensive care unit. A large number of epidemiological changes have …

Biological potential and medical use of secondary metabolites

AML Seca, DCGA Pinto - Medicines, 2019 - mdpi.com
This Medicines special issue focuses on the great potential of secondary metabolites for
therapeutic applications. The special issue contains 16 articles reporting relevant …

Exploring the use of cannabis as a substitute for prescription drugs in a convenience sample

SL Kvamme, MM Pedersen, K Rømer Thomsen… - Harm reduction …, 2021 - Springer
Background The use of cannabis as medicine (CaM) both prescribed and non-prescribed
has increased markedly in the last decade, mirrored in a global shift in cannabis policy …

[HTML][HTML] Lower urinary tract symptoms in depression: a review

DJ Anderson, A Aucoin, CR Toups… - Health psychology …, 2023 - ncbi.nlm.nih.gov
Abstract Lower Urinary Tract Symptoms (LUTS) are frequently present in the general
population as patients age with approximately a third of individuals experiencing LUTS …

An individuality of response to cannabinoids: challenges in safety and efficacy of cannabis products

S Kitdumrongthum, D Trachootham - Molecules, 2023 - mdpi.com
Since legalization, cannabis/marijuana has been gaining considerable attention as a
functional ingredient in food.∆-9 tetrahydrocannabinol (THC), cannabidiol (CBD), and other …

Cannabis use in pregnant and breastfeeding women: behavioral and neurobiological consequences

F Navarrete, MS García-Gutiérrez, A Gasparyan… - Frontiers in …, 2020 - frontiersin.org
Nowadays, cannabis is the most consumed illicit drug. The global prevalence of the use of
cannabis in 2017 was estimated in 188 million of people, 3.8% of worldwide population …