Artificial intelligence, healthcare, clinical genomics, and pharmacogenomics approaches in precision medicine

H Abdelhalim, A Berber, M Lodi, R Jain, A Nair… - Frontiers in …, 2022 - frontiersin.org
Precision medicine has greatly aided in improving health outcomes using earlier diagnosis
and better prognosis for chronic diseases. It makes use of clinical data associated with the …

Precision medicine with multi-omics strategies, deep phenotyping, and predictive analysis

Z Ahmed - Progress in molecular biology and translational …, 2022 - Elsevier
Precision medicine is driven by the paradigm shift of empowering clinicians to predict the
most appropriate course of action for patients with complex diseases and to improve routine …

Practicing precision medicine with intelligently integrative clinical and multi-omics data analysis

Z Ahmed - Human genomics, 2020 - Springer
Precision medicine aims to empower clinicians to predict the most appropriate course of
action for patients with complex diseases like cancer, diabetes, cardiomyopathy, and COVID …

Human gene and disease associations for clinical‐genomics and precision medicine research

Z Ahmed, S Zeeshan, D Mendhe… - Clinical and translational …, 2020 - Wiley Online Library
We are entering the era of personalized medicine in which an individual's genetic makeup
will eventually determine how a doctor can tailor his or her therapy. Therefore, it is becoming …

[HTML][HTML] Investigating genes associated with heart failure, atrial fibrillation, and other cardiovascular diseases, and predicting disease using machine learning …

V Venkat, H Abdelhalim, W DeGroat, S Zeeshan… - Genomics, 2023 - Elsevier
Cardiovascular disease (CVD) is the leading cause of mortality and loss of disability
adjusted life years (DALYs) globally. CVDs like Heart Failure (HF) and Atrial Fibrillation (AF) …

Multi-omics strategies for personalized and predictive medicine: past, current, and future translational opportunities

Z Ahmed - Emerging topics in life sciences, 2022 - portlandpress.com
Precision medicine is driven by the paradigm shift of empowering clinicians to predict the
most appropriate course of action for patients with complex diseases and improve routine …

Advancing clinical genomics and precision medicine with GVViZ: FAIR bioinformatics platform for variable gene-disease annotation, visualization, and expression …

Z Ahmed, EG Renart, S Zeeshan, XQ Dong - Human genomics, 2021 - Springer
Background Genetic disposition is considered critical for identifying subjects at high risk for
disease development. Investigating disease-causing and high and low expressed genes …

RNA-seq driven expression and enrichment analysis to investigate CVD genes with associated phenotypes among high-risk heart failure patients

Z Ahmed, S Zeeshan, BT Liang - Human genomics, 2021 - Springer
Background Heart failure (HF) is one of the most common complications of cardiovascular
diseases (CVDs) and among the leading causes of death in the US. Many other CVDs can …

Genomics pipelines to investigate susceptibility in whole genome and exome sequenced data for variant discovery, annotation, prediction and genotyping

Z Ahmed, EG Renart, S Zeeshan - PeerJ, 2021 - peerj.com
Over the last few decades, genomics is leading toward audacious future, and has been
changing our views about conducting biomedical research, studying diseases, and …

Intelligent health system for the investigation of consenting COVID-19 patients and precision medicine

Z Ahmed - Personalized medicine, 2021 - Taylor & Francis
Advancing frontiers of clinical research, we discuss the need for intelligent health systems to
support a deeper investigation of COVID-19. We hypothesize that the convergence of the …