Inactivating mutations of the tumor suppressor gene Liver Kinase B1 (LKB1) are frequently
detected in non‐small‐cell lung cancer (NSCLC) and cervical carcinoma. Moreover, LKB1 …

Over time, more and more is becoming known about micro-players of great significance.
This is particularly the case for microRNAs (miRNAs; miR), which have been found to …

The subset of regulatory T (Treg) cells, with its specific transcription Foxp3, is a unique cell
type for the maintenance of immune homeostasis by controlling effector T (Teff) cell …

Abstract miRNAs are a class of non-coding RNAs and very conserve molecules that
negatively regulate the expression of many genes by targeting the 3′ UTR of mRNAs …

Being responsible for almost 12% of cancers worldwide, viruses are among the oldest
known and most prevalent oncogenic agents. The quality of the evidence for the in vivo …

The risk of developing adult T-cell leukemia/lymphoma (ATLL) in individuals infected with
human T-cell lymphotropic virus 1 (HTLV-1) is about 3–5%. The mechanisms by which the …

Human T cell leukemia virus type 1 (HTLV-1) was identified as the first pathogenic human
retrovirus and is estimated to infect 5 to 10 million individuals worldwide. Unlike other …

MicroRNAs (miRNAs) are noncoding RNAs that participate in the pathophysiology of
depression by targeting many functional genes. As shown in our previous study, chronic …

Background Adult T cell lymphoma/leukemia (ATLL) is a peripheral T-cell neoplasm caused
by human T-cell lymphotropic virus-1 (HTLV-1). Small RNAs (sRNAs), including microRNAs …

MicroRNAs (miRs) are a group of small, 17–25 nucleotide, non-coding RNA that regulate
gene expression at the post-transcriptional level. To date, little is known about the molecular …