Construction of Smart DNA‐Based Drug Delivery Systems for Cancer Therapy

C Li, M Wang, PF Li, J Sheng, Q Fu - Small, 2024 - Wiley Online Library
Due to the disadvantages of poor targeting, slow action, and low effectiveness of current
commonly used cancer treatments, including surgery, chemotherapy, and radiotherapy …

Adhesive AuNP tape-mediated hierarchical assembly of multicenter DNA nanocomplexes for tumor cell nucleus-targeted staged drug delivery in vivo

C Li, Y Gao, Q Li, S Luo, W Liao, ZS Wu - Nano Today, 2022 - Elsevier
Developing DNA nanostructures as delivery vectors into organelles is a key technical barrier
because of their innate poor pharmacokinetic properties. Herein, we propose a unique …

[HTML][HTML] DNA tetrahedral nanostructures for the biomedical application and spatial orientation of biomolecules

W Wang, M Lin, W Wang, Z Shen, ZS Wu - Bioactive Materials, 2024 - Elsevier
DNA not only plays a vital role in nature as fundamental hereditary material for storing
genetic material, but also serves as well-defined functional material, for example, building …

[HTML][HTML] Gold nanosystems covered with doxorubicin/DNA complexes: A therapeutic target for prostate and liver cancer

RM Giráldez-Pérez, E Grueso… - International Journal of …, 2022 - mdpi.com
Different gold nanosystems covered with DNA and doxorubicin (Doxo) were designed and
synthesized for cancer therapy, starting from Au@ 16-Ph-16 cationic nanoparticles and DNA …

Self‐Reinforced Bimetallic Mito‐Jammer for Ca2+ Overload‐Mediated Cascade Mitochondrial Damage for Cancer Cuproptosis Sensitization

C Du, X Guo, X Qiu, W Jiang, X Wang, H An… - Advanced …, 2024 - Wiley Online Library
Overproduction of reactive oxygen species (ROS), metal ion accumulation, and tricarboxylic
acid cycle collapse are crucial factors in mitochondria‐mediated cell death. However, the …

Intelligent Reconfiguration‐Promoted Cellular Internalization of Core–Shell DNA Nanoprobe Equipped with Successive Dual Stimuli‐Responsive Protective Satellites …

W Pan, H Niu, S Luo, L Chen, ZS Wu - Small, 2024 - Wiley Online Library
Although DNA probes have attracted increasing interest for precise tumor cell identification
by imaging intracellular biomarkers, the requirement of commercial transfection reagents …

Chitosan Based Hybrid Polymeric Systems in Diabetes Monitoring

L Kaur, Neelam, YA Hajam, R Kumar, MS Reshi… - Chitosan …, 2023 - Springer
Diabetes is an endocrinometabolic disorder caused due to the irregular glucose
metabolism. Insulin is secreted by pancreatic islets of β-cells. Hence, the pancreas is known …