Smart nanoparticles for cancer therapy
Smart nanoparticles, which can respond to biological cues or be guided by them, are
emerging as a promising drug delivery platform for precise cancer treatment. The field of …
emerging as a promising drug delivery platform for precise cancer treatment. The field of …
The evolution of commercial drug delivery technologies
Drug delivery technologies have enabled the development of many pharmaceutical
products that improve patient health by enhancing the delivery of a therapeutic to its target …
products that improve patient health by enhancing the delivery of a therapeutic to its target …
[HTML][HTML] Natural products in drug discovery: advances and opportunities
AG Atanasov, SB Zotchev, VM Dirsch… - Nature reviews Drug …, 2021 - nature.com
Natural products and their structural analogues have historically made a major contribution
to pharmacotherapy, especially for cancer and infectious diseases. Nevertheless, natural …
to pharmacotherapy, especially for cancer and infectious diseases. Nevertheless, natural …
[HTML][HTML] Discovery and resupply of pharmacologically active plant-derived natural products: A review
AG Atanasov, B Waltenberger… - Biotechnology …, 2015 - Elsevier
Medicinal plants have historically proven their value as a source of molecules with
therapeutic potential, and nowadays still represent an important pool for the identification of …
therapeutic potential, and nowadays still represent an important pool for the identification of …
Pinpointing secondary metabolites that shape the composition and function of the plant microbiome
RP Jacoby, A Koprivova… - Journal of Experimental …, 2021 - academic.oup.com
One of the major questions in contemporary plant science involves determining the
functional mechanisms that plants use to shape their microbiome. Plants produce a plethora …
functional mechanisms that plants use to shape their microbiome. Plants produce a plethora …
[HTML][HTML] Development of botanicals to combat antibiotic resistance
PD Gupta, TJ Birdi - Journal of Ayurveda and integrative medicine, 2017 - Elsevier
The discovery of antibiotics in the previous century lead to reduction in mortality and
morbidity due to infectious diseases but their inappropriate and irrational use has resulted in …
morbidity due to infectious diseases but their inappropriate and irrational use has resulted in …
Natural products for human health: an historical overview of the drug discovery approaches
S Bernardini, A Tiezzi, V Laghezza Masci… - Natural product …, 2018 - Taylor & Francis
Natural products (NPs) are secondary metabolites produced and used by organisms for
defending or adapting purposes. These molecules were naturally selected during thousands …
defending or adapting purposes. These molecules were naturally selected during thousands …
An analysis of FDA-approved drugs: natural products and their derivatives
E Patridge, P Gareiss, MS Kinch, D Hoyer - Drug discovery today, 2016 - Elsevier
Highlights•Natural products contribute more than one-third of all FDA-approved NMEs.•The
absolute number of natural product approvals peaked in the 1990s and has since …
absolute number of natural product approvals peaked in the 1990s and has since …
Plant derived substances with anti-cancer activity: from folklore to practice
M Fridlender, Y Kapulnik, H Koltai - Frontiers in plant science, 2015 - frontiersin.org
Plants have had an essential role in the folklore of ancient cultures. In addition to the use as
food and spices, plants have also been utilized as medicines for over 5000 years. It is …
food and spices, plants have also been utilized as medicines for over 5000 years. It is …
The pharmaceutical industry and natural products: historical status and new trends
Owing to the high diversity of terrestrial and marine organisms, natural products (secondary
metabolites) are some of the most successful source of drug leads for the treatment of many …
metabolites) are some of the most successful source of drug leads for the treatment of many …