Oral microbiota in human systematic diseases

X Peng, L Cheng, Y You, C Tang, B Ren, Y Li… - International journal of …, 2022 - nature.com
Oral bacteria directly affect the disease status of dental caries and periodontal diseases. The
dynamic oral microbiota cooperates with the host to reflect the information and status of …

Periodontal inflammation and systemic diseases: an overview

M Martínez-García, E Hernández-Lemus - Frontiers in physiology, 2021 - frontiersin.org
Periodontitis is a common inflammatory disease of infectious origins that often evolves into a
chronic condition. Aside from its importance as a stomatologic ailment, chronic periodontitis …

The role of microbiota in infant health: from early life to adulthood

Y Yao, X Cai, Y Ye, F Wang, F Chen… - Frontiers in …, 2021 - frontiersin.org
From early life to adulthood, the microbiota play a crucial role in the health of the infant. The
microbiota in early life are not only a key regulator of infant health but also associated with …

Periodontal microorganisms and Alzheimer disease–A causative relationship?

G Jungbauer, A Stähli, X Zhu… - Periodontology …, 2022 - Wiley Online Library
In the initiation or exacerbation of Alzheimer disease, the dissemination of oral
microorganisms into the brain tissue or the low‐level systemic inflammation have been …

Oral–gut microbiome axis in gastrointestinal disease and cancer

SY Park, BO Hwang, M Lim, SH Ok, SK Lee, KS Chun… - Cancers, 2021 - mdpi.com
Simple Summary Microbiota dysbiosis is correlated with numerous diseases in the human
body. To date, the research on the microbiome-associated diseases been focused on an …

Application of ligature-induced periodontitis in mice to explore the molecular mechanism of periodontal disease

P Lin, H Niimi, Y Ohsugi, Y Tsuchiya… - International journal of …, 2021 - mdpi.com
Periodontitis is an inflammatory disease characterized by the destruction of the
periodontium. In the last decade, a new murine model of periodontitis has been widely used …

Gingipain-Responsive Thermosensitive Hydrogel Loaded with SDF-1 Facilitates In Situ Periodontal Tissue Regeneration

S Liu, YN Wang, B Ma, J Shao, H Liu… - ACS Applied Materials & …, 2021 - ACS Publications
Existing local drug delivery systems for periodontitis suffer from poor antibacterial effect and
unsatisfied periodontal regeneration. In this study, a smart gingipain-responsive hydrogel …

Porphyromonas gingivalis Virulence Factors and Clinical Significance in Periodontal Disease and Coronary Artery Diseases

LH Aleksijević, M Aleksijević, I Škrlec, M Šram, M Šram… - Pathogens, 2022 - mdpi.com
Porphyromonas gingivalis is a gram-negative, anaerobic bacterium that lives in the oral
cavity. It is an integral part of the oral microbiome, which includes more than 500 types of …

Porphyromonas gingivalis regulates atherosclerosis through an immune pathway

Q Ruan, P Guan, W Qi, J Li, M Xi, L Xiao… - Frontiers in …, 2023 - frontiersin.org
Atherosclerosis (AS) is a chronic inflammatory disease, involving a pathological process of
endothelial dysfunction, lipid deposition, plaque rupture, and arterial occlusion, and is one of …

Porphyromonas gingivalis and Lactobacillus rhamnosus GG regulate the Th17/Treg balance in colitis via TLR4 and TLR2

L Jia, R Wu, N Han, J Fu, Z Luo, L Guo… - Clinical & …, 2020 - Wiley Online Library
Objectives CD4+ T cells are the key to many immune–inflammatory diseases mediated by
microbial disorders, especially inflammatory bowel disease (IBD). The purpose of this study …