A key aspect for successful drug delivery via lipid‐based nanoparticles is their
internalization in target cells. Two prominent examples of such drug delivery systems are …

Autoimmunity is defined by the presence of antibodies and/or T cells directed against self-
components. Although of unknown etiology, autoimmunity commonly is associated with …

Deeper understanding of T-cell-mediated adaptive immune responses is important for the
design of cancer immunotherapies and antiviral vaccines against pandemic outbreaks. T …

Infectious diseases are a burden for aquaculture. Antigen processing and presentation
(APP) to the immune effector cells that fight pathogens is key in the adaptive immune …

Cell surface HLA-I molecules (Face-1) consist of a polypeptide heavy chain (HC) with two
groove domains (G domain) and one constant domain (C-domain) as well as a light chain …

Type 1 diabetes mellitus (T1DM) is an autoimmune disease resulting from loss of insulin-
secreting β-cells in islets of Langerhans. The loss of β-cells is initiated when self-tolerance to …

Macrophages have a wide variety of roles in physiological and pathological conditions,
making them promising diagnostic and therapeutic targets in diseases, especially metabolic …

Cartilaginous fish are the most primitive extant species with MHC molecules. Using the
nurse shark, the current study is, to the best of our knowledge, the first to present a peptide …

Ganglioside GM3 is one of the most common membrane-bound glycosphingolipids. The
over-expression of GM3 on tumor cells makes it defined as a tumor-associated carbohydrate …

DLA-88 is a classical major histocompatibility complex (MHC) class I gene in dogs, and
allelic DLA-88 molecules have been divided into two categories named “DLA-88* 0” and …