The impact of ACE and ACE2 gene polymorphisms in pulmonary diseases including COVID-19

I Gintoni, M Adamopoulou, C Yapijakis - in vivo, 2022 - iv.iiarjournals.org
Chronic and acute respiratory diseases pose a major problem for public health worldwide
due to the high morbidity and mortality rates, while treatment options remain mostly …

Angiotensin converting enzyme inhibitors and angiotensin receptor blockers: a promising medication for chronic obstructive pulmonary disease?

IE Vasileiadis, CA Goudis… - COPD: Journal of …, 2018 - Taylor & Francis
Chronic obstructive pulmonary disease (COPD) is a complex disorder that primarily affects
the lungs and is characterized not only by local pulmonary, but also by systemic …

Angiotensin converting enzyme genotypes and mortality from COVID-19: An ecological study

AK Aung, T Aitken, BM Teh, C Yu, R Ofori-Asenso… - Journal of Infection, 2020 - Elsevier
Background Angiotensin converting enzyme (ACE) genotypes are known to be associated
with development of acute respiratory distress syndrome (ARDS) and resultant mortality. In …

ACE gene I/D polymorphism and arterial hypertension in patients with COPD

M Marushchak, K Maksiv, I Krynytska - Pneumologia, 2019 - sciendo.com
Background: Cardiovascular diseases (CVDs) are common in people with chronic
obstructive pulmonary disease (COPD), and their presence is associated with an increased …

Promoter Polymorphism (−308G/A) of Tumor Necrosis Factor-Alpha (TNF-α) Gene and Asthma Risk: An Updated Meta-Analysis

SW Kang, SK Kim, YR Han, DW Hong… - Genetic testing and …, 2019 - liebertpub.com
Background and Aims: The relationship between the promoter polymorphism (− 308G/A) of
the tumor necrosis factor-alpha (TNF-α) gene and the susceptibility to asthma has been …

Could patients with chronic obstructive pulmonary disease benefit from renin angiotensin system inhibitors? A meta-analysis

H Lv, J Huang, M Miao, C Huang… - BMJ Open …, 2023 - bmjopenrespres.bmj.com
Background Chronic obstructive pulmonary disease (COPD) is considered related to chronic
systemic inflammation. Renin angiotensin system (RAS) inhibitor, exerting an anti …

Factors associated with acceptability, consideration and intention of uptake of direct-to-consumer genetic testing: a survey study

KFJ Stewart, D Kokole, A Wesselius… - Public Health …, 2019 - karger.com
Background: With interest in personalised health care growing, so is interest in personal
genetic testing. This is now offered direct-to-consumer, thereby referred to as direct-to …

Association of angiotensin-converting enzyme gene I/D polymorphism with chronic obstructive pulmonary disease: a meta-analysis

G Xu, G Fan, Y Sun, L Yu, S Wu… - Journal of the Renin …, 2018 - journals.sagepub.com
Objectives: We conducted a meta-analysis of published studies on the angiotensin-
converting enzyme (ACE) gene insertion/deletion (I/D) polymorphism associated with the …

[PDF][PDF] The role of insertion-deletion polymorphism of the ACE gene in development of arterial hypertension in patients with chronic obstructive pulmonary disease

M Marushchak, K Maksiv, I Krynytska… - Bangladesh Journal of …, 2020 - researchgate.net
Objective. This study aims to establish the role of insertion-deletion polymorphism of the
angiotensin-converting enzyme gene in development of arterial hypertension in patients …

[HTML][HTML] Insertion/deletion polymorphism of angiotensin-converting enzyme and chronic obstructive pulmonary disease: A case-control study on north Indian …

N Kirtipal, H Thakur, RC Sobti - Molecular Biology Research …, 2019 - ncbi.nlm.nih.gov
This research aimed to explore the ACE (insertion/deletion) gene association as key factor
for chronic obstructive pulmonary disease (COPD) development in north Indian population …