Sleep deprivation refers to an intentional or unintentional reduction in sleep time, resulting in
insufficient sleep. It is often caused by sleep disorders, work demands (eg, night shifts), and …

Background The main manifestation of Alzheimer's disease (AD) in patients and animal
models is impaired memory function, characterized by amyloid-beta (Aβ) deposition and …

Sleep deprivation (SD) has reached epidemic proportions worldwide and negatively affects
people of all ages. Cognitive impairment induced by SD involves neuroinflammation and …

Sleep deprivation (SD) has a profound impact on the central nervous system, resulting in an
array of mood disorders, including depression and anxiety. Despite this, the dynamic …

Background: Emerging evidence indicates that sleep disorders are the common non-
cognitive symptoms of Alzheimer's disease (AD), and they may contribute to the …

Sleep deprivation (SD) is a hallmark of modern society and associated with many
neuropsychiatric disorders, including depression and anxiety. However, the cellular and …

Transcranial alternating current stimulation (tACS) is considered to have a positive effect on
the rehabilitation of Alzheimer's disease (AD) as an intervention method that matches …

Neurodegenerative disorders, such as Alzheimer's disease (AD), have the gradual onset of
neurobiological changes preceding clinical diagnosis by decades. To elucidate how brain …

Dexmedetomidine (DEX) is a highly selective α2-adrenoceptor agonist with sedative effects
on sleep homeostasis. Oxytocin-expressing (OXT) neurons in the paraventricular nucleus …

目的研究咖啡因(CAF) 对睡眠剥夺(SD) 模型大鼠睡眠时相, γ 振荡和免疫系统功能的影响.
方法Wistar 大鼠分为正常对照组, SD 组和SD+ CAF 组. 除正常对照组外, 其余各组利用跑台式 …