Colouring agents are highly present in diverse products in the human environment. We
aimed to elucidate the fibrogenic cascade triggered by the food dyes tartrazine and …

Objective: The mechanisms responsible for increased collagen production and hepatic
fibrosis in biliary atresia (BA) remain largely unknown. We evaluated α-smooth muscle actin …

To detect the expression of pro-fibrotic molecules, such as heat shock protein 47 (Hsp47),
transforming growth factor-beta 1 (TGF-β1) and connective tissue growth factor (CTGF) in …

Background In biliary atresia mechanisms of progressive liver injury leading to need of liver
transplantation after successful portoenterostomy remain unknown. A better understanding …

Introduction. Non-alcoholic fatty liver disease (NAFLD) is a common chronic liver disease
which becomes a rapidly growing health problem in the Western countries. The …

AIM: To study the relation between collagen 1, α-smooth muscle actin (α-SMA) and CD34
expression and the most essential portoenterostomy (PE) outcomes. METHODS: Liver …

Background Pathogenesis of progressive liver fibrosis in biliary atresia after successful
portoenterostomy remains unclear. We related hepatic expression of transforming growth …

Objectives: Our previous work demonstrated altered messenger RNA expression of integrin
β-5 and-8, using an in silico analysis of publically available data from patients with biliary …

Purpose We describe a new rat model of biliary atresia, induced by biliary ablation with pure
ethanol. Methods A catheter was inserted and fixed in the common bile duct of male rats …

Biliary atresia (BA), blockage of the proper bile flow due to loss of extrahepatic bile ducts, is
a rare, complex disease of the liver and the bile ducts with unknown etiology. Despite …