The role of cytochrome P450s in insect toxicology and resistance

R Nauen, C Bass, R Feyereisen… - Annual Review of …, 2022 - annualreviews.org
Insect cytochrome P450 monooxygenases (P450s) perform a variety of important
physiological functions, but it is their role in the detoxification of xenobiotics, such as natural …

[HTML][HTML] A review of the molecular mechanisms of acaricide resistance in mites and ticks

S De Rouck, E İnak, W Dermauw… - Insect Biochemistry and …, 2023 - Elsevier
Abstract The Arachnida subclass of Acari comprises many harmful pests that threaten
agriculture as well as animal health, including herbivorous spider mites, the bee parasite …

[HTML][HTML] Functional and structural diversity of insect glutathione S-transferases in xenobiotic adaptation

SK BK, T Moural, F Zhu - International journal of biological sciences, 2022 - ncbi.nlm.nih.gov
As a superfamily of multifunctional enzymes that is mainly associated with xenobiotic
adaptation, glutathione S-transferases (GSTs) facilitate insects' survival under chemical …

A nuclear receptor HR96-related gene underlies large trans-driven differences in detoxification gene expression in a generalist herbivore

M Ji, M Vandenhole, B De Beer, S De Rouck… - Nature …, 2023 - nature.com
The role, magnitude, and molecular nature of trans-driven expression variation underlying
the upregulation of detoxification genes in pesticide resistant arthropod populations has …

Pesticide resistance in arthropods: Ecology matters too

A Bras, A Roy, DG Heckel, P Anderson… - Ecology …, 2022 - Wiley Online Library
Pesticide resistance development is an example of rapid contemporary evolution that poses
immense challenges for agriculture. It typically evolves due to the strong directional …

Insecticide resistance in the Cydia pomonella (L): Global status, mechanisms, and research directions

D Ju, D Mota-Sanchez, E Fuentes-Contreras… - Pesticide biochemistry …, 2021 - Elsevier
The codling moth, Cydia pomonella (Lepidoptera: Tortricidae) is a major pest of pome fruit
and walnuts worldwide. Although environmentally compatible integrated control strategies …

Resistance in the Genus Spodoptera: Key Insect Detoxification Genes

F Hilliou, T Chertemps, M Maïbèche, G Le Goff - Insects, 2021 - mdpi.com
Simple Summary The moth larvae are among the most damaging pest species on crops
worldwide. In this review, we focus on the genus Spodoptera, which can feed on many crops …

Transcription Factor AhR Regulates Glutathione S-Transferases Conferring Resistance to lambda-Cyhalothrin in Cydia pomonella

C Hu, YX Liu, SP Zhang, YQ Wang, P Gao… - Journal of Agricultural …, 2023 - ACS Publications
Aryl hydrocarbon receptor (AhR) enhances insect resistance to insecticides by regulating
the detoxification network. Our previous studies have confirmed that overexpressions of …

Dynamic roles of insect carboxyl/cholinesterases in chemical adaptation

C Cruse, TW Moural, F Zhu - Insects, 2023 - mdpi.com
Simple Summary Carboxyl/cholinesterases (CCEs) represent a family of enzymes
distributed in many organisms, including insects. Despite their relatively simple catalyzed …

The pleiotropic AMPK–CncC signaling pathway regulates the trade-off between detoxification and reproduction

H Jiang, X Meng, N Zhang, H Ge… - Proceedings of the …, 2023 - National Acad Sciences
The association of decreased fecundity with insecticide resistance and the negative
sublethal effects of insecticides on insect reproduction indicates the typical trade-off between …