Rotavirus replication and virulence are strongly influenced by virus strain and host species.
The rotavirus proteins VP3, VP4, VP7, NSP1, and NSP4 have all been implicated in strain …

Objectives: Biliary atresia (BA) is a rapidly progressive form of biliary fibrosis affecting
neonates. We previously reported that primary cilia on the intrahepatic cholangiocytes of …

Cholangiocytes function as antigen-presenting cells with CD1d-dependent activation of
natural killer T (NKT) cells in vitro. NKT cells may act both pro-and anti-inflammatory in liver …

The liver is a vital organ with distinctive anatomy, histology and heterogeneous cell
populations. These characteristics are of particular importance in maintaining immune …

Biliary atresia (BA) is a neonatal disease that results in obliteration of the biliary tree. The
murine model of BA, which mirrors the human disease, is based upon infection of newborn …

Biliary atresia is a rare inflammatory sclerosing obstructive cholangiopathy that initiates in
infancy as complete choledochal blockage and progresses to the involvement of …

Background Biliary atresia (BA) is the most common indication for liver transplantation in
children. The experimental model of BA, induced by rotavirus infection in neonatal mice, has …

Biliary atresia (BA) is a progressive, inflammatory, and fibrosclerosing cholangiopathy in
infants that results in obstruction of both extrahepatic and intrahepatic bile ducts. It is the …

Methods: Lymphocytes from the liver and extrahepatic bile duct remnants of patients with
biliary atresia were characterized by immunofluorescence staining, fluorescence-activated …

Biliary atresia (BA) is a devastating cholestatic liver disease targeting infants. Current
diagnosis depends on surgical exploration of the biliary tree. The aim of the present study …