The potential role of leptin in tumor invasion and metastasis

A Ray, MP Cleary - Cytokine & growth factor reviews, 2017 - Elsevier
The adipocyte-released hormone-like cytokine/adipokine leptin behaves differently in
obesity compared to its functions in the normal healthy state. In obese individuals, elevated …

Suppressing fatty acid uptake has therapeutic effects in preclinical models of prostate cancer

MJ Watt, AK Clark, LA Selth, VR Haynes… - Science translational …, 2019 - science.org
Metabolism alterations are hallmarks of cancer, but the involvement of lipid metabolism in
disease progression is unclear. We investigated the role of lipid metabolism in prostate …

[HTML][HTML] Breast Tomographic Ultrasound: The Spectrum from Current Dense Breast Cancer Screenings to Future Theranostic Treatments

PJ Littrup, M Mehrmohammadi, N Duric - Tomography, 2024 - mdpi.com
This review provides unique insights to the scientific scope and clinical visions of the
inventors and pioneers of the SoftVue breast tomographic ultrasound (BTUS). Their> 20 …

Early detection breast cancer: role of circulating plasma miRNA-21 expression as apotential screening biomarker

MN Diansyah, AA Prayogo… - Turkish Journal of …, 2021 - journals.tubitak.gov.tr
Aim: To explore the potential of the circulating plasma miRNA-21 as an early detection
biomarker by comparing early-stage breast cancer (BG) and healthy control (HG) in …

Deep learning-based multi-label tissue segmentation and density assessment from mammograms

VM Tiryaki, V Kaplanoğlu - IRBM, 2022 - Elsevier
Objectives: Breast cancer is the most commonly diagnosed type of cancer among women
and a common cause of cancer-related deaths. Early diagnosis and treatment of breast …

The fat-glandular interface and breast tumor locations: Appearances on ultrasound tomography are supported by quantitative peritumoral analyses

PJ Littrup, N Duric, M Sak, C Li, O Roy… - Journal of Breast …, 2021 - academic.oup.com
Objective To analyze the preferred tissue locations of common breast masses in relation to
anatomic quadrants and the fat-glandular interface (FGI) using ultrasound tomography …

Fatty acid composition in mammary adipose tissue measured by Gradient-echo Spectroscopic MRI and its association with breast cancers

AA Lewin, P Storey, M Moccaldi, L Moy… - European journal of …, 2019 - Elsevier
Purpose To assess the association of fatty acid levels in mammary adipose tissue of
postmenopausal women with the presence of breast cancer using the Gradient-echo …

A conditional inference tree model for predicting cancer risk of non-mass lesions detected on breast ultrasound

X Wang, L Jing, L Yan, P Wang, C Zhao, H Xu… - European Radiology, 2023 - Springer
Objectives To generate and validate a prediction model based on imaging features for
cancer risk of non-mass lesions (NMLs) detected on breast ultrasound (US). Methods In this …

Quantitative analysis of peri-tumor fat in different molecular subtypes of breast cancer

JH Chen, Y Zhang, S Chan, RF Chang… - Magnetic resonance …, 2018 - Elsevier
Background and purposes The aim of this study was to develop morphological analytic
methods to analyze the tumor-fat interface and in different peritumoral shells away from the …

[HTML][HTML] The potential role of the fat–glandular interface (FGI) in breast carcinogenesis: Results from an ultrasound tomography (UST) study

N Duric, M Sak, PJ Littrup - Journal of Clinical Medicine, 2021 - mdpi.com
This study explored the relationship between the extent of the fat–glandular interface (FGI)
and the presence of malignant vs. benign lesions. Two hundred and eight patients were …