Iron overload increases the production of harmful reactive oxygen species in the Fenton
reaction, which causes oxidative stress in the body and lipid peroxidation in the cell …

Abstract Sepsis-associated encephalopathy (SAE), a common neurological complication of
sepsis, is a heterogenous complex clinical syndrome caused by the dysfunctional response …

Diabetic cardiomyopathy (DCM) is one serious and common complication in diabetes
without effective treatments. Hydrogen sulfide (H 2 S) fights against a variety of …

The three striatins (STRN, STRN3, STRN4) form the core of STR iatin-I nteracting P
hosphatase and K inase (STRIPAK) complexes. These place protein phosphatase 2A …

Cardiac myocyte death is an essential initiator of the pathogenesis and progression of
various etiological cardiomyopathies, including diabetic cardiomyopathy (DCM), a disease …

Sepsis-associated encephalopathy (SAE) is a prevalent complication of sepsis, with
hippocampal neuroinflammation playing a crucial role in SAE-induced cognitive impairment …

Cuproptosis is a recently reported new mode of programmed cell death which might be a
potential co-pathogenesis of three kinds of primary cardiomyopathy. However, no …

Regulated cell death (RCD) represents a distinct mode of cell demise, differing from
accidental cell death (ACD), characterized by specific signaling cascades orchestrated by …

Diabetic cardiomyopathy, a multifaceted complication of diabetes mellitus, remains a major
challenge in clinical management due to its intricate pathophysiology. Emerging evidence …

The term cardiomyopathy refers to a group of heart diseases that cause severe heart failure
over time. Cardiomyopathies have been proven to be associated with ferroptosis, a non …