The role of microRNAs in the pathophysiology of human central nervous system: a focus on neurodegenerative diseases

D Rezaee, F Saadatpour, N Akbari, A Zoghi… - Ageing Research …, 2023 - Elsevier
Abstract microRNAs (miRNAs) are suggested to play substantial roles in regulating the
development and various physiologic functions of the central nervous system (CNS). These …

Non-coding RNAs/DNMT3B axis in human cancers: from pathogenesis to clinical significance

C Huang, P Azizi, M Vazirzadeh… - Journal of Translational …, 2023 - Springer
Cancer is a complex disease with many contributing factors, and researchers have gained
extensive knowledge that has helped them understand the diverse and varied nature of …

microRNA-184 in the landscape of human malignancies: a review to roles and clinical significance

M Fattahi, D Rezaee, F Fakhari, S Najafi… - Cell Death …, 2023 - nature.com
MicroRNAs (miRNAs) are a class of non-coding RNAs (ncRNAs) with a short length of 19–
22 nucleotides. miRNAs are posttranscriptional regulators of gene expression involved in …

Liquid biopsy in colorectal cancer

S Najafi, J Majidpoor, K Mortezaee - Clinica Chimica Acta, 2023 - Elsevier
Liquid biopsy refers to a set of pathological samples retrieved from non-solid sources, such
as blood, cerebrospinal fluid, urine, and saliva through non-invasive or minimally invasive …

Microbiome modulation in inflammatory diseases: Progress to microbiome genetic engineering

F Mousavinasab, R Karimi, S Taheri… - Cancer Cell …, 2023 - Springer
Recent developments in sequencing technology and analytical approaches have allowed
researchers to show that the healthy gut microbiome is very varied and capable of …

Exosomal miR-122-3p represses the growth and metastasis of MCF-7/ADR cells by targeting GRK4-mediated activation of the Wnt/β-catenin pathway

B Song, G Hou, M Xu, M Chen - Cellular Signalling, 2024 - Elsevier
Breast cancer (BC) is a common cancer whose incidence continues to grow while its
medical progress has stagnated. miRNAs are vital messengers that facilitate …

Tumor-educated platelets

S Najafi, Y Asemani, J Majidpoor, R Mahmoudi… - Clinica Chimica …, 2023 - Elsevier
Beyond traditional roles in homeostasis and coagulation, growing evidence suggests that
platelets also reflect malignant transformation in cancer. Platelets are present in the tumor …

A pro-death autophagy-based nanoplatform for enhancing antitumour efficacy with improved immune responses

Y Li, X Du, X Kong, Y Fang, Z He, D Liu, H Wu… - European Journal of …, 2024 - Elsevier
Due to the pro-survival effect of mild autophagy, the therapeutic effect of chemo-
immunotherapy is unsatisfactory. In addition, the adverse tumour microenvironment (TME) …

Circulating vitamin D level before initiating chemotherapy impacts on the time-to-outcome in metastatic colorectal cancer patients: systematic review and meta …

A Ottaiano, ML Iacovino, M Santorsola… - Journal of Translational …, 2024 - Springer
Abstract Background Vitamin D (VD) is implicated in various health conditions, including
colorectal cancer (CRC). To investigate potential relationships between pre-chemotherapy …

Revolutionizing colorectal cancer treatment: unleashing the potential of miRNAs in targeting cancer stem cells

GY Osei, J Adu-Amankwaah, S Koomson… - Future …, 2023 - Taylor & Francis
Colorectal cancer (CRC) is a significant contributor to cancer mortality worldwide, and the
presence of cancer stem cells (CSC) represents a major challenge for achieving effective …