[HTML][HTML] An Update on Drug–Nutrient Interactions and Dental Decay in Older Adults

V Bell, AR Rodrigues, M Antoniadou, M Peponis… - Nutrients, 2023 - mdpi.com
In recent decades, the global demographic landscape has undergone a discernible shift that
has been characterised by a progressive increase in the proportion of elderly individuals …

Assessment and management of pain, with particular emphasis on central neuropathic pain, in moderate to severe dementia

EJA Scherder, B Plooij - Drugs & aging, 2012 - Springer
In patients with dementia, undertreatment of pain, irrespective of its aetiology, is widely
recognized; the risk for undertreatment increases with the severity of dementia. We argue …

Two multicenter, 8-week, randomized, double-blind, placebo-controlled, parallel-group studies evaluating the efficacy and tolerability of amlodipine and valsartan in …

T Philipp, TR Smith, R Glazer, M Wernsing, J Yen… - Clinical …, 2007 - Elsevier
BACKGROUND:: Patients with hypertension may require combination therapy to attain the
blood pressure targets recommended by US and European treatment guidelines …

Tolerability and blood pressure-lowering efficacy of the combination of amlodipine plus valsartan compared with lisinopril plus hydrochlorothiazide in adult patients …

D Poldermans, R Glazes, S Kargiannis, M Wernsing… - Clinical …, 2007 - Elsevier
BACKGROUND:: Most patients with hypertension in the United States and Europe fail to
achieve the recomended target blood pressure (BP) of< 140/90 mm Hg. Combination …

Optimization of controlled release nanoparticle formulation of verapamil hydrochloride using artificial neural networks with genetic algorithm and response surface …

Y Li, MR Abbaspour, PV Grootendorst… - European Journal of …, 2015 - Elsevier
This study was performed to optimize the formulation of polymer–lipid hybrid nanoparticles
(PLN) for the delivery of an ionic water-soluble drug, verapamil hydrochloride (VRP) and to …

CaV1.3 L-type Ca2+ channels modulate depression-like behaviour in mice independent of deaf phenotype

P Busquet, N Khoi Nguyen, E Schmid… - International Journal …, 2010 - academic.oup.com
Mounting evidence suggests that voltage-gated L-type Ca2+ channels can modulate
affective behaviour. We therefore explored the role of CaV1. 3 L-type Ca2+ channels in …

Point-of-care detection and real-time monitoring of intravenously delivered drugs via tubing with an integrated SERS sensor

HY Wu, BT Cunningham - Nanoscale, 2014 - pubs.rsc.org
We demonstrate an approach for detection, identification, and kinetic monitoring of drugs
flowing within tubing, through the use of a plasmonic nanodome array (PNA) surface. The …

[HTML][HTML] The Evolving Role of Calcium Channel Blockers in Hypertension Management: Pharmacological and Clinical Considerations

KE Jones, SL Hayden, HR Meyer, JL Sandoz… - Current Issues in …, 2024 - mdpi.com
Worldwide, hypertension is the leading risk factor for cardiovascular disease and death. An
estimated 122 million people, per the American Heart Association in 2023, have been …

Modified-release nifedipine: a review of the use of modified-release formulations in the treatment of hypertension and angina pectoris

KF Croom, K Wellington - Drugs, 2006 - Springer
Nifedipine is a dihydropyridine calcium channel antagonist with predominantly vasodilatory
activity. Modified-release formulations of nifedipine are effective antihypertensive and …

[HTML][HTML] A novel high content angiogenesis assay reveals that Lacidipine, L-type calcium channel blocker, induces in vitro vascular lumen expansion

DA Nawrot, LY Ozer, A Al Haj Zen - International Journal of Molecular …, 2022 - mdpi.com
Angiogenesis is a critical cellular process toward establishing a functional circulatory system
capable of delivering oxygen and nutrients to the tissue in demand. In vitro angiogenesis …