[PDF][PDF] An unbiased screen for human cytomegalovirus identifies neuropilin-2 as a central viral receptor

N Martinez-Martin, J Marcandalli, CS Huang, CP Arthur… - Cell, 2018 - cell.com
Characterizing cell surface receptors mediating viral infection is critical for understanding
viral tropism and developing antiviral therapies. Nevertheless, due to challenges associated …

An overview on enrichment methods for cell surface proteome profiling

Y Li, H Qin, M Ye - Journal of separation science, 2020 - Wiley Online Library
Cell surface proteins are essential for many important biological processes, including cell–
cell interactions, signal transduction, and molecular transportation. With the characteristics of …

[PDF][PDF] The immunoglobulin superfamily receptome defines cancer-relevant networks associated with clinical outcome

E Verschueren, B Husain, K Yuen, Y Sun, S Paduchuri… - Cell, 2020 - cell.com
Cell surface receptors and their interactions play a central role in physiological and
pathological signaling. Despite its clinical relevance, the immunoglobulin superfamily (IgSF) …

A host–microbiota interactome reveals extensive transkingdom connectivity

ND Sonnert, CE Rosen, AR Ghazi, EA Franzosa… - Nature, 2024 - nature.com
The myriad microorganisms that live in close association with humans have diverse effects
on physiology, yet the molecular bases for these impacts remain mostly unknown …

[PDF][PDF] Homeostatic functions of monocytes and interstitial lung macrophages are regulated via collagen domain-binding receptor LAIR1

S Keerthivasan, Y Şenbabaoğlu, N Martinez-Martin… - Immunity, 2021 - cell.com
Myeloid cells encounter stromal cells and their matrix determinants on a continual basis
during their residence in any given organ. Here, we examined the impact of the collagen …

Mapping the Human Cell Surface Interactome: A Key to Decode Cell-to-Cell Communication

J Shilts, GJ Wright - Annual Review of Biomedical Data Science, 2024 - annualreviews.org
Proteins on the surfaces of cells serve as physical connection points to bridge one cell with
another, enabling direct communication between cells and cohesive structure. As …

A platform for extracellular interactome discovery identifies novel functional binding partners for the immune receptors B7-H3/CD276 and PVR/CD155

B Husain, SR Ramani, E Chiang, I Lehoux… - Molecular & Cellular …, 2019 - ASBMB
Receptors expressed on the plasma membrane and their interacting partners critically
regulate cellular communication during homeostasis and disease, and as such represent …

A membrane protein display platform for receptor interactome discovery

S Cao, SM Peterson, S Müller… - Proceedings of the …, 2021 - National Acad Sciences
Cell surface receptors are critical for cell signaling and constitute a quarter of all human
genes. Despite their importance and abundance, receptor interaction networks remain …

Identification of orphan ligand-receptor relationships using a cell-based CRISPRa enrichment screening platform

DH Siepe, LT Henneberg, SC Wilson, GT Hess… - Elife, 2022 - elifesciences.org
Secreted proteins, which include cytokines, hormones, and growth factors, are extracellular
ligands that control key signaling pathways mediating cell-cell communication within and …

Comprehensive discovery of the accessible primary amino group-containing segments from cell surface proteins by fine-tuning a high-throughput biotinylation method

T Langó, K Kuffa, G Tóth, L Turiák, L Drahos… - International Journal of …, 2022 - mdpi.com
Cell surface proteins, including transmembrane and other surface-anchored proteins, play a
key role in several critical cellular processes and have a strong diagnostic value. The …