Understanding the dynamic of the proteome is a critical challenge because it requires high
sensitive methodologies in high-throughput formats in order to decipher its modifications …

The cellular surfaceome and its residing extracellularly exposed proteins are involved in a
multitude of molecular signaling processes across the viral infection cycle. Successful viral …

The extracellular matrix (ECM) forms of a three dimensional interaction network mostly
comprised of proteins, collagens being the most abundant ones (Ricard-Blum, Cold Spring …

Technological improvements in unbiased screening have accelerated drug target discovery.
In particular, membrane-embedded and secreted proteins have gained attention because of …

Membrane protein interactions are challenging to identify because of the unique biophysical
characteristics of both transmembrane proteins and membrane environments. The Receptor …

Large-scale visualization and analysis of HPIs involved in microbial CVDs can provide
crucial insights into the mechanisms of pathogenicity. The comparison of CVD associated …

This is a story about how it is possible for collections of cells to physically assemble into
coordinated multicellular systems. In other words, how millions of individual cells are able to …

Bacteria utilize complement regulators as a means of evading the host immune response.
Here, we describe protocols for evaluating the role vitronectin acquisition at the bacterial cell …

Receptors expressed on the plasma membrane and their interacting partners critically
regulate cellular communication during homeostasis and disease, and as such represent …

Any microorganism which is capable of bringing illness in a host organism is termed as
pathogen. Pathogens manipulate the cellular mechanisms of host organisms via pathogen …