[HTML][HTML] Tackling the glial scar in spinal cord regeneration: new discoveries and future directions
Axonal regeneration and functional recovery are poor after spinal cord injury (SCI), typified
by the formation of an injury scar. While this scar was traditionally believed to be primarily …
by the formation of an injury scar. While this scar was traditionally believed to be primarily …
Alzheimer's disease and clinical trials
D Paul, R Agrawal, S Singh - … of Basic and Clinical Physiology and …, 2024 - degruyter.com
Alzheimer's disease (AD) is spreading its root disproportionately among the worldwide
population. Many genes have been identified as the hallmarks of AD. Based upon the …
population. Many genes have been identified as the hallmarks of AD. Based upon the …
Microtubule-binding protein MAP1B regulates interstitial axon branching of cortical neurons via the tubulin tyrosination cycle
J Ziak, JM Dorskind, B Trigg, S Sudarsanam… - The EMBO …, 2024 - embopress.org
Regulation of directed axon guidance and branching during development is essential for the
generation of neuronal networks. However, the molecular mechanisms that underlie …
generation of neuronal networks. However, the molecular mechanisms that underlie …
HIF-1α Induced by Hypoxia Promotes Peripheral Nerve Injury Recovery Through Regulating Ferroptosis in DRG Neuron
S An, J Shi, J Huang, Z Li, M Feng, G Cao - Molecular Neurobiology, 2024 - Springer
Peripheral nerve injury (PNI) usually has a poor effect on functional recovery and severely
declines the patient's quality of life. Our prior findings indicated that hypoxia remarkably …
declines the patient's quality of life. Our prior findings indicated that hypoxia remarkably …
[HTML][HTML] Calcium-Associated Proteins in Neuroregeneration
The dysregulation of intracellular calcium levels is a critical factor in neurodegeneration,
leading to the aberrant activation of calcium-dependent processes and, ultimately, cell …
leading to the aberrant activation of calcium-dependent processes and, ultimately, cell …
Netrin-1 As A Neural Guidance Protein In Development And Reinnervation Of The Larynx
I Hernandez-Morato, S Koss, E Honzel… - Annals of Anatomy …, 2024 - Elsevier
Neural guidance proteins participate in motor neuron migration, axonal projection, and
muscle fiber innervation during development. One of the guidance proteins that participates …
muscle fiber innervation during development. One of the guidance proteins that participates …
Intellectual Disability and Behavioral Deficits Linked to CYFIP1 Missense Variants Disrupting Actin Polymerization
Abstract Background 15q11. 2 deletions and duplications have been linked to autism
spectrum disorder, schizophrenia, and intellectual disability. Recent evidence suggests that …
spectrum disorder, schizophrenia, and intellectual disability. Recent evidence suggests that …
[HTML][HTML] MAP1B Regulates Cortical Neuron Interstitial Axon Branching Through the Tubulin Tyrosination Cycle
J Ziak, J Dorskind, B Trigg, S Sudarsanam, R Hand… - bioRxiv, 2023 - ncbi.nlm.nih.gov
Regulation of directed axon guidance and branching during development is essential for the
generation of neuronal networks. However, the molecular mechanisms that underlie …
generation of neuronal networks. However, the molecular mechanisms that underlie …
Exosomes promote axon outgrowth and a polarized neuronal morphology by engaging the Wnt-Planar Cell Polarity pathway
S Ahmad, M Pye, M Narimatsu, S Song, T Christova… - bioRxiv, 2023 - biorxiv.org
In neurons, the acquisition of a polarized morphology is achieved upon the outgrowth of a
single axon from one of several neurites. Exosomes from diverse sources are known to …
single axon from one of several neurites. Exosomes from diverse sources are known to …
Qualitative Observations of Transgenically Individualized Serotonergic Fibers in the Mouse Telencephalon
JH Haiman, KC Mays, HA Roostaeyan, N Elyasi… - bioRxiv, 2023 - biorxiv.org
The matrix of serotonergic axons (fibers) is a constant feature of neural tissue in vertebrate
brains. Its fundamental role appears to be associated with the spatiotemporal control of …
brains. Its fundamental role appears to be associated with the spatiotemporal control of …