[HTML][HTML] Tackling the glial scar in spinal cord regeneration: new discoveries and future directions

A Shafqat, I Albalkhi, HM Magableh, T Saleh… - Frontiers in Cellular …, 2023 - frontiersin.org
Axonal regeneration and functional recovery are poor after spinal cord injury (SCI), typified
by the formation of an injury scar. While this scar was traditionally believed to be primarily …

Alzheimer's disease and clinical trials

D Paul, R Agrawal, S Singh - … of Basic and Clinical Physiology and …, 2024 - degruyter.com
Alzheimer's disease (AD) is spreading its root disproportionately among the worldwide
population. Many genes have been identified as the hallmarks of AD. Based upon the …

Microtubule-binding protein MAP1B regulates interstitial axon branching of cortical neurons via the tubulin tyrosination cycle

J Ziak, JM Dorskind, B Trigg, S Sudarsanam… - The EMBO …, 2024 - embopress.org
Regulation of directed axon guidance and branching during development is essential for the
generation of neuronal networks. However, the molecular mechanisms that underlie …

HIF-1α Induced by Hypoxia Promotes Peripheral Nerve Injury Recovery Through Regulating Ferroptosis in DRG Neuron

S An, J Shi, J Huang, Z Li, M Feng, G Cao - Molecular Neurobiology, 2024 - Springer
Peripheral nerve injury (PNI) usually has a poor effect on functional recovery and severely
declines the patient's quality of life. Our prior findings indicated that hypoxia remarkably …

[HTML][HTML] Calcium-Associated Proteins in Neuroregeneration

M Lisek, J Tomczak, T Boczek, L Zylinska - Biomolecules, 2024 - mdpi.com
The dysregulation of intracellular calcium levels is a critical factor in neurodegeneration,
leading to the aberrant activation of calcium-dependent processes and, ultimately, cell …

Netrin-1 As A Neural Guidance Protein In Development And Reinnervation Of The Larynx

I Hernandez-Morato, S Koss, E Honzel… - Annals of Anatomy …, 2024 - Elsevier
Neural guidance proteins participate in motor neuron migration, axonal projection, and
muscle fiber innervation during development. One of the guidance proteins that participates …

Intellectual Disability and Behavioral Deficits Linked to CYFIP1 Missense Variants Disrupting Actin Polymerization

V Mariano, AK Kanellopoulos, C Ricci, D Di Marino… - Biological …, 2024 - Elsevier
Abstract Background 15q11. 2 deletions and duplications have been linked to autism
spectrum disorder, schizophrenia, and intellectual disability. Recent evidence suggests that …

[HTML][HTML] MAP1B Regulates Cortical Neuron Interstitial Axon Branching Through the Tubulin Tyrosination Cycle

J Ziak, J Dorskind, B Trigg, S Sudarsanam, R Hand… - bioRxiv, 2023 - ncbi.nlm.nih.gov
Regulation of directed axon guidance and branching during development is essential for the
generation of neuronal networks. However, the molecular mechanisms that underlie …

Exosomes promote axon outgrowth and a polarized neuronal morphology by engaging the Wnt-Planar Cell Polarity pathway

S Ahmad, M Pye, M Narimatsu, S Song, T Christova… - bioRxiv, 2023 - biorxiv.org
In neurons, the acquisition of a polarized morphology is achieved upon the outgrowth of a
single axon from one of several neurites. Exosomes from diverse sources are known to …

Qualitative Observations of Transgenically Individualized Serotonergic Fibers in the Mouse Telencephalon

JH Haiman, KC Mays, HA Roostaeyan, N Elyasi… - bioRxiv, 2023 - biorxiv.org
The matrix of serotonergic axons (fibers) is a constant feature of neural tissue in vertebrate
brains. Its fundamental role appears to be associated with the spatiotemporal control of …