[HTML][HTML] Metalloproteinases and their inhibitors: potential for the development of new therapeutics

M Raeeszadeh-Sarmazdeh, LD Do, BG Hritz - Cells, 2020 - mdpi.com
The metalloproteinase (MP) family of zinc-dependent proteases, including matrix
metalloproteinases (MMPs), a disintegrin and metalloproteases (ADAMs), and a disintegrin …

Free radical as a double-edged sword in disease: Deriving strategic opportunities for nanotherapeutics

L Zhu, M Luo, Y Zhang, F Fang, M Li, F An… - Coordination Chemistry …, 2023 - Elsevier
Free radicals, usually containing one or more unpaired electrons, are extremely unstable
and highly reactive with other biological molecules. Recently, there has been increasing …

[HTML][HTML] Impacts of triglyceride-glucose index on prognosis of patients with type 2 diabetes mellitus and non-ST-segment elevation acute coronary syndrome: results …

Q Zhao, TY Zhang, YJ Cheng, Y Ma, YK Xu… - Cardiovascular …, 2020 - Springer
Background The relationship between triglyceride-glucose index (TyG index) and the
prevalence and prognosis of cardiovascular disease has been confirmed by former studies …

[HTML][HTML] Positive association between triglyceride glucose index and arterial stiffness in hypertensive patients: the China H-type Hypertension Registry Study

M Li, A Zhan, X Huang, L Hu, W Zhou, T Wang… - Cardiovascular …, 2020 - Springer
Background Data are limited on whether TyG index is an independent predictor of arterial
stiffness in hypertensive patients. The purpose of this study was to assess the association …

[HTML][HTML] Impact of diabetes mellitus on clinical outcomes in patients affected by Covid-19

C Sardu, G Gargiulo, G Esposito, G Paolisso… - Cardiovascular …, 2020 - Springer
A possible association could exist between type 2 diabetes mellitus (T2DM) and
Coronavirus-19 (Covid-19) infection. Indeed, patients with T2DM show high prevalence …

Safeguarding osteointegration in diabetic patients: a potent “Chain Armor” Coating for scavenging ROS and macrophage reprogramming in a microenvironment …

Q He, S Yuan, H Tang, S Wang, Z Mu… - Advanced Functional …, 2021 - Wiley Online Library
Risk of implant failure increases profoundly in patients with pre‐existing conditions (eg,
diabetes). Current therapies adopt a one‐sided focus on the direct antibacterial properties of …

[HTML][HTML] Coagulatory defects in type-1 and type-2 diabetes

AIS Sobczak, AJ Stewart - International journal of molecular sciences, 2019 - mdpi.com
Diabetes (both type-1 and type-2) affects millions of individuals worldwide. A major cause of
death for individuals with diabetes is cardiovascular diseases, in part since both types of …

[HTML][HTML] Ellagic acid as a tool to limit the diabetes burden: Updated evidence

AJ Amor, C Gómez-Guerrero, E Ortega, A Sala-Vila… - Antioxidants, 2020 - mdpi.com
Oxidative stress contributes not only to the pathogenesis of type 2 diabetes (T2D) but also to
diabetic vascular complications. It follows that antioxidants might contribute to limiting the …

[HTML][HTML] Association between METS-IR and prehypertension or hypertension among normoglycemia subjects in Japan: a retrospective study

KY Han, J Gu, Z Wang, J Liu, S Zou, CX Yang… - Frontiers in …, 2022 - frontiersin.org
Aim Our study aimed to investigate the association between the novel non–insulin‐based
metabolic score for insulin resistance (METS-IR) index and pre-hypertension (HTN) or HTN …

[HTML][HTML] The atherogenic index of plasma plays an important role in predicting the prognosis of type 2 diabetic subjects undergoing percutaneous coronary …

Z Qin, K Zhou, Y Li, W Cheng, Z Wang, J Wang… - Cardiovascular …, 2020 - Springer
Background Many studies have reported the predictive value of the atherogenic index of
plasma (AIP) in the progression of atherosclerosis and the prognosis of percutaneous …